GBA Regulates EMT/MET and Chemoresistance in Squamous Cell Carcinoma Cells by Modulating the Cellular Glycosphingolipid Profile

Glycosphingolipids (GSL) are plasma membrane components that influence molecular processes involved in cancer initiation, progression, and therapeutic responses. They also modulate receptor tyrosine kinases involved in EMT. Therefore, understanding the mechanisms that regulate GSLs in cancer has imp...

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Bibliographic Details
Main Authors:	Laura E. Clark, Amanda J. G. Dickinson, Santiago Lima
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Cells
Subjects:	glucosylceramide gangliosides squamous cell carcinoma chemoresistance EMT MET
Online Access:	https://www.mdpi.com/2073-4409/12/14/1886

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