Leishmania promastigotes: building a safe niche within macrophages

Leishmania promastigotes: building a safe niche within macrophages

Upon their internalization by macrophages, Leishmania promastigotes inhibit phagolysosome biogenesis. The main factor responsible for this inhibition is the promastigote surface glycolipid lipophosphoglycan (LPG). This glycolipid has a profound impact on the phagosome, causing periphagosomal accum...

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Bibliographic Details
Main Authors:	Neda eMoradin, Albert eDescoteaux
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-09-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	Leishmania Virulence lipophosphoglycan macrophage phagosome
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00121/full

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