HPLC with Post-Column Derivatization with Alizarin for Determination of OATD-02, an Anticancer Arginase Inhibitor in Clinical Development

HPLC with Post-Column Derivatization with Alizarin for Determination of OATD-02, an Anticancer Arginase Inhibitor in Clinical Development

The aim of this study was to develop an analytical method for selective determination of OATD-02 by high-performance liquid chromatography (HPLC) with post-column derivatization and fluorescence detection (FLD). OATD-02, a new boronic acid derivative, is a highly potent anticancer arginase inhibitor...

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Bibliographic Details
Main Authors:	Elzbieta Sobolewska, Magdalena Tyszkiewicz, Roman Blaszczyk, Magdalena Biesaga
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Series:	Applied Sciences
Subjects:	post-column derivatization active pharmaceutical ingredient arginase inhibitor HPLC
Online Access:	https://www.mdpi.com/2076-3417/13/16/9201

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