The metabolome of Mexican cavefish shows a convergent signature highlighting sugar, antioxidant, and Ageing-Related metabolites

The metabolome of Mexican cavefish shows a convergent signature highlighting sugar, antioxidant, and Ageing-Related metabolites

Insights from organisms, which have evolved natural strategies for promoting survivability under extreme environmental pressures, may help guide future research into novel approaches for enhancing human longevity. The cave-adapted Mexican tetra, Astyanax mexicanus, has attracted interest as a model...

Full description

Bibliographic Details
Main Authors:	J Kyle Medley, Jenna Persons, Tathagata Biswas, Luke Olsen, Robert Peuß, Jaya Krishnan, Shaolei Xiong, Nicolas Rohner
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-06-01
Series:	eLife
Subjects:	Astyanax mexicanus cavefish metabolomics resilience ageing non-traditional model
Online Access:	https://elifesciences.org/articles/74539

Similar Items

Convergence on reduced aggression through shared behavioral traits in multiple populations of Astyanax mexicanus
by: Roberto Rodriguez-Morales, et al.
Published: (2022-10-01)

Genetic mapping of metabolic traits in the blind Mexican cavefish reveals sex-dependent quantitative trait loci associated with cave adaptation
by: Misty R. Riddle, et al.
Published: (2021-05-01)

Reduced Oxygen as an Environmental Pressure in the Evolution of the Blind Mexican Cavefish
by: Tyler Boggs, et al.
Published: (2021-01-01)

Astyanax surface and cave fish morphs
by: William R. Jeffery
Published: (2020-07-01)

Phenotypic plasticity as a mechanism of cave colonization and adaptation
by: Helena Bilandžija, et al.
Published: (2020-04-01)

Pescoids and Chimeras to Probe Early Evo-Devo in the Fish Astyanax mexicanus
by: Jorge Torres-Paz, et al.
Published: (2021-04-01)

Asymmetric Facial Bone Fragmentation Mirrors Asymmetric Distribution of Cranial Neuromasts in Blind Mexican Cavefish
by: Joshua B. Gross, et al.
Published: (2016-10-01)

Microbiome differences between river-dwelling and cave-adapted populations of the fish Astyanax mexicanus (De Filippi, 1853)
by: Patricia Ornelas-García, et al.
Published: (2018-11-01)

Cavefishes in Chronobiological Research: A Narrative Review
by: Vera V. Pavlova, et al.
Published: (2023-02-01)

Evidence for rapid divergence of sensory systems between Texas populations of the Mexican tetra (Astyanax mexicanus)
by: Maya S. Enriquez, et al.
Published: (2023-02-01)

The evolution of a series of behavioral traits is associated with autism-risk genes in cavefish
by: Masato Yoshizawa, et al.
Published: (2018-06-01)

Maternally regulated gastrulation as a source of variation contributing to cavefish forebrain evolution
by: Jorge Torres-Paz, et al.
Published: (2019-10-01)

Hypocretin underlies the evolution of sleep loss in the Mexican cavefish
by: James B Jaggard, et al.
Published: (2018-02-01)

Social-like responses are inducible in asocial Mexican cavefish despite the exhibition of strong repetitive behavior
by: Motoko Iwashita, et al.
Published: (2021-09-01)

An Adult Brain Atlas Reveals Broad Neuroanatomical Changes in Independently Evolved Populations of Mexican Cavefish
by: Cody Loomis, et al.
Published: (2019-10-01)

Developmental evolution of the forebrain in cavefish, from natural variations in neuropeptides to behavior
by: Alexandre Alié, et al.
Published: (2018-02-01)

A brain-wide analysis maps structural evolution to distinct anatomical module
by: Robert A Kozol, et al.
Published: (2023-07-01)

Complete mitochondrial genome of a cavefish Sinocyclocheilus ronganensis (Cypriniformes: Cyprinidae)
by: Fuguang Luo, et al.
Published: (2017-01-01)

Extraoral expression and characterization of bitter taste receptors in Astyanax mexicanus (Mexican tetra fish)
by: Vikram Bhatia, et al.
Published: (2022-09-01)

Validating two-dimensional leadership models on three-dimensionally structured fish schools
by: Isobel Watts, et al.
Published: (2017-01-01)

Metabolic shift toward ketosis in asocial cavefish increases social-like affinity
by: Motoko Iwashita, et al.
Published: (2023-10-01)

Unlocking the Secrets of the Regenerating Fish Heart: Comparing Regenerative Models to Shed Light on Successful Regeneration
by: Helen G. Potts, et al.
Published: (2021-01-01)

Comparative transcriptomics reveals the molecular genetic basis of pigmentation loss in Sinocyclocheilus cavefishes
by: Chunqing Li, et al.
Published: (2020-12-01)

Unravelling the origins of boldness behaviour: a common garden experiment with cavefish (Barbatula barbatula)
by: Jolle W. Jolles, et al.
Published: (2024-01-01)

Evidence for late Pleistocene origin of Astyanax mexicanus cavefish
by: Julien Fumey, et al.
Published: (2018-04-01)

Transcriptomic analysis of the Brazilian blind characid, Stygichthys typhlops, reveals convergent selection with Astyanax mexicanus and other cavefishes
by: Dahiana Arcila, et al.
Published: (2023-05-01)

The nature and distribution of putative non-functional alleles suggest only two independent events at the origins of Astyanax mexicanus cavefish populations
by: Maxime Policarpo, et al.
Published: (2024-04-01)

Unique sperm haplotypes are associated with phenotypically different sperm subpopulations in Astyanax fish
by: Richard Borowsky, et al.
Published: (2018-07-01)

Evolutionary convergence of a neural mechanism in the cavefish lateral line system
by: Elias T Lunsford, et al.
Published: (2022-06-01)

PacBio Full-Length Transcriptome of a Tetraploid <i>Sinocyclocheilus multipunctatus</i> Provides Insights into the Evolution of Cavefish
by: Renyi Zhang, et al.
Published: (2023-11-01)

Cavefish cope with environmental hypoxia by developing more erythrocytes and overexpression of hypoxia-inducible genes
by: Corine M van der Weele, et al.
Published: (2022-01-01)

Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method
by: Helen G. Potts, et al.
Published: (2022-02-01)

Genetic structure and historical and contemporary gene flow of Astyanaxmexicanus in the Gulf of Mexico slope: a microsatellite-based analysis
by: Rodolfo Pérez-Rodríguez, et al.
Published: (2021-02-01)

Chromosomal analysis of Astyanax fasciatus (PISCES, CHARACIDAE) from the Araguari river, Uberlândia, MG, Brazil
by: A. R. Torres-Mariano, et al.

Apparent effect of chronic Plasmodium infections on disease severity caused by experimental infections with Mycoplasma gallisepticum in house finches
by: André A. Dhondt, et al.
Published: (2017-08-01)

Genetic mapping of craniofacial traits in the Mexican tetra reveals loci associated with bite differences between cave and surface fish
by: Amanda K. Powers, et al.
Published: (2023-08-01)

Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation
by: Jaya Krishnan, et al.
Published: (2022-06-01)

Two new species of Astyanax (Ostariophysi: Characiformes: Characidae) from eastern Brazil, with a synopsis of the Astyanax scabripinnis species complex
by: Vinicius A. Bertaco, et al.

Astyanax guaricana (Ostariophysi: Characidae), a new species from the rio Cubatão drainage, Paraná State, Southern Brazil
by: Carlos A. M. Oliveira, et al.

Two new species of Aristocleidus (Monogenea) from the gills of the Mexican mojarra Eugerres mexicanus (Perciformes, Gerreidae) from southwestern Mexico
by: Mendoza-Franco Edgar F., et al.
Published: (2015-01-01)