Nitro-Group-Containing Thiopeptide Derivatives as Promising Agents to Target <i>Clostridioides difficile</i>

Nitro-Group-Containing Thiopeptide Derivatives as Promising Agents to Target <i>Clostridioides difficile</i>

The US Centers for Disease Control and Prevention (CDC) lists <i>Clostridioides difficile</i> as an urgent bacterial threat. Yet, only two drugs, vancomycin and fidaxomicin, are approved by the FDA for the treatment of <i>C. difficile</i> infections as of this writing, while...

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Bibliographic Details
Main Authors: Dahyun Kim, Young-Rok Kim, Hee-Jong Hwang, Marco A. Ciufolini, Jusuk Lee, Hakyeong Lee, Shyaka Clovis, Sungji Jung, Sang-Hun Oh, Young-Jin Son, Jin-Hwan Kwak
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
<i>Clostridioides difficile</i>
thiopeptide antibiotics
nitro-group-containing antibiotics
Online Access:https://www.mdpi.com/1424-8247/15/5/623

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