Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

Abstract Background As a subclass of endogenous stable noncoding RNAs, circular RNAs are beginning to be appreciated for their potential as tumor therapeutics. However, the functions and mechanisms by which circRNAs exert protective functions in non-small cell lung cancer (NSCLC) remain largely elus...

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Bibliographic Details
Main Authors: Deze Zhao, Yeping Dong, Minghao Duan, Dan He, Qun Xie, Wei Peng, Weifang Cui, Junjie Jiang, Yuanda Cheng, Heng Zhang, Faqing Tang, Chunfang Zhang, Yang Gao, Chaojun Duan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Non-small cell lung cancer
circGUCY1A2
miR-200c-3p
PTEN
ARNTL
Online Access:https://doi.org/10.1186/s13046-023-02791-1

Internet

https://doi.org/10.1186/s13046-023-02791-1

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