Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis

ObjectiveTo compare the outcomes of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis in 1–2 cm size.MethodsThe clinical data of patients with multiple renal calculi in the range of 1–2 CM who underwent flexible ureteroscopy lithotripsy and per...

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Main Authors: Guangda Lv, Zhiwei Zhang, Fei Du, Wenqiang Qi, Minglei Zhong, Yongheng Zhou, Changkuo Zhou, Yan Li, Dongqing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004432/full
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author Guangda Lv
Zhiwei Zhang
Fei Du
Wenqiang Qi
Minglei Zhong
Yongheng Zhou
Changkuo Zhou
Yan Li
Dongqing Zhang
author_facet Guangda Lv
Zhiwei Zhang
Fei Du
Wenqiang Qi
Minglei Zhong
Yongheng Zhou
Changkuo Zhou
Yan Li
Dongqing Zhang
author_sort Guangda Lv
collection DOAJ
description ObjectiveTo compare the outcomes of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis in 1–2 cm size.MethodsThe clinical data of patients with multiple renal calculi in the range of 1–2 CM who underwent flexible ureteroscopy lithotripsy and percutaneous nephrolithotomy in Qilu Hospital of Shandong University from January 2016 to March 2021 were retrospectively collected and matched using propensity score matching. Then a subgrouping of the number of stones was performed. Patients were divided into Group A and Group B according to their stone numbers. Patients with no statistically significant differences in baseline data were matched to compare the safety and efficacy of the two procedures.ResultsA total of 210 patients with clinical data were collected, and the patients’ baseline data were not comparable, and 142 patients were finally included in the study after propensity score matching. There was no statistical difference in baseline data between the two groups of patients. The postoperative hospital days (3.00, 2.00 vs. 7.00, 3.00, P < 0.001), operation time (90.00, 50.00 vs. 110.00, 53.00, P = 0.018), complications (6, 6.8% vs. 14, 25.9%, P = 0.001) of patients in flexible ureteroscopy group %, P = 0.001) was significantly lower than that in the percutaneous nephrolithotomy group. There was no significant difference in stone clearance rate between the two groups (76, 86.4% vs. 42, 77.8%, P = 0.185). When the number of stones was no more than 3, the operation time (85.00, 49.00 vs. 110.00, 53.00, P = 0.005) and complications (2, 4.2% vs. 11, 29.7%, P = 0.001) of f-URS were significantly less than those of mPCNL, but when the number of stones was more than 3, there was no significant difference between the two operations.ConclusionFor multiple nephrolithiasis within 1–2 CM, when the number of stones does not exceed 3, flexible ureteroscopy can achieve the same stone clearance rate as percutaneous nephrolithotomy, while having shorter post-operation days, operative time and fewer complications. When the number of stones is more than 3, there are no significant difference between two operations.
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spelling doaj.art-8f0411b4b55e482894e56bea1aa212632022-12-22T03:12:48ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-09-01910.3389/fsurg.2022.10044321004432Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasisGuangda Lv0Zhiwei Zhang1Fei Du2Wenqiang Qi3Minglei Zhong4Yongheng Zhou5Changkuo Zhou6Yan Li7Dongqing Zhang8Department of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Yanggu People’s Hospital, Yanggu, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaDepartment of Urology, Qilu Hospital of Shandong University, Jinan, ChinaObjectiveTo compare the outcomes of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis in 1–2 cm size.MethodsThe clinical data of patients with multiple renal calculi in the range of 1–2 CM who underwent flexible ureteroscopy lithotripsy and percutaneous nephrolithotomy in Qilu Hospital of Shandong University from January 2016 to March 2021 were retrospectively collected and matched using propensity score matching. Then a subgrouping of the number of stones was performed. Patients were divided into Group A and Group B according to their stone numbers. Patients with no statistically significant differences in baseline data were matched to compare the safety and efficacy of the two procedures.ResultsA total of 210 patients with clinical data were collected, and the patients’ baseline data were not comparable, and 142 patients were finally included in the study after propensity score matching. There was no statistical difference in baseline data between the two groups of patients. The postoperative hospital days (3.00, 2.00 vs. 7.00, 3.00, P < 0.001), operation time (90.00, 50.00 vs. 110.00, 53.00, P = 0.018), complications (6, 6.8% vs. 14, 25.9%, P = 0.001) of patients in flexible ureteroscopy group %, P = 0.001) was significantly lower than that in the percutaneous nephrolithotomy group. There was no significant difference in stone clearance rate between the two groups (76, 86.4% vs. 42, 77.8%, P = 0.185). When the number of stones was no more than 3, the operation time (85.00, 49.00 vs. 110.00, 53.00, P = 0.005) and complications (2, 4.2% vs. 11, 29.7%, P = 0.001) of f-URS were significantly less than those of mPCNL, but when the number of stones was more than 3, there was no significant difference between the two operations.ConclusionFor multiple nephrolithiasis within 1–2 CM, when the number of stones does not exceed 3, flexible ureteroscopy can achieve the same stone clearance rate as percutaneous nephrolithotomy, while having shorter post-operation days, operative time and fewer complications. When the number of stones is more than 3, there are no significant difference between two operations.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004432/fullflexible ureteroscopymini-percutaneous nephrolithotomyupper urinary tract calculipropensity score matchinglithotripsy
spellingShingle Guangda Lv
Zhiwei Zhang
Fei Du
Wenqiang Qi
Minglei Zhong
Yongheng Zhou
Changkuo Zhou
Yan Li
Dongqing Zhang
Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
Frontiers in Surgery
flexible ureteroscopy
mini-percutaneous nephrolithotomy
upper urinary tract calculi
propensity score matching
lithotripsy
title Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
title_full Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
title_fullStr Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
title_full_unstemmed Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
title_short Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
title_sort comparison of flexible ureteroscopy and mini percutaneous nephrolithotomy in the treatment for multiple nephrolithiasis
topic flexible ureteroscopy
mini-percutaneous nephrolithotomy
upper urinary tract calculi
propensity score matching
lithotripsy
url https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004432/full
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