New Trimethoprim-Like Molecules: Bacteriological Evaluation and Insights into Their Action

New Trimethoprim-Like Molecules: Bacteriological Evaluation and Insights into Their Action

This work reports a detailed characterization of the antimicrobial profile of two trimethoprim-like molecules (compounds <b>1a</b> and <b>1b</b>) identified in previous studies. Both molecules displayed remarkable antimicrobial activity, particularly when combined with sulfam...

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Bibliographic Details
Main Authors:	Marta Jorba, Marina Pedrola, Ouldouz Ghashghaei, Rocío Herráez, Lluis Campos-Vicens, Franciso Javier Luque, Rodolfo Lavilla, Miguel Viñas
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Antibiotics
Subjects:	trimethoprim multidrug-resistant (MDR) bacteria mechanisms of action dihydrofolate reductase
Online Access:	https://www.mdpi.com/2079-6382/10/6/709

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