Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool
Abstract Background The mental health and quality of life in children with asthma have attracted widespread attention. This study focused on the evaluation of mental health conditions and their clinical characteristics in Chinese children with asthma. Methods A total of 261 children with asthma aged...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-11-01
|
| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12887-019-1834-7 |
| _version_ | 1818346003926876160 |
|---|---|
| author | Hao Zhou Zhihe Chen Weiqing Zhao Ye Liu Yuxia Cui |
| author_facet | Hao Zhou Zhihe Chen Weiqing Zhao Ye Liu Yuxia Cui |
| author_sort | Hao Zhou |
| collection | DOAJ |
| description | Abstract Background The mental health and quality of life in children with asthma have attracted widespread attention. This study focused on the evaluation of mental health conditions and their clinical characteristics in Chinese children with asthma. Methods A total of 261 children with asthma aged 6 to 16 years old and 261 age- and gender-matched children from the general population were recruited to participate in this study from Guizhou Provincial People’s Hospital. The parents of all subjects were interviewed using the MINI Kid and were required to finish a clinical characteristics questionnaire. Logistic regression analysis was performed to evaluate risk factors. Results The prevalence of mental health conditions in the asthma group was significantly higher than that in the control group (26.4% vs 14.6%, P < 0.001). A total of 10 mental health conditions was identified in the asthma group, the most common of which was ADHD (11.5%; 30/261), followed by oppositional defiant disorder (ODD) (10.7%; 28/261), separation anxiety disorder (6.1%; 16/261), social anxiety disorder (3.8%; 10/261), specific phobias (2.3%; 6/261), agoraphobia without panic (1.5%; 4/261), (mild) manic episodes (1.1%; 3/261), major depressive episodes (MDEs) (0.8%; 2/261), movement (tic) disorder (0.8%; 2/261), and dysthymia (0.4%; 1/261). A total of 6 neuropsychiatric conditions was detected in the control group, including ODD (5.7%; 15/261), ADHD (4.6%; 12/261), social anxiety disorder (3.1%; 8/261), seasonal anxiety disorder (SAD) (2.3%; 6/261), specific phobias (1.1%; 3/261), and agoraphobia without panic (0.4%; 1/261). The prevalence rates of ODD, ADHD, and SAD differed significantly between the two groups (P < 0.05). Multiple regression analysis revealed that severe persistent asthma (OR = 3.077, 95% CI 1.286–7.361), poor asthma control (OR = 2.005, 95% CI 1.111–3.619), and having asthma for > 3 years (OR = 2.948, 95% CI 1.580–5.502) were independent risk factors for the presence of mental health conditions in asthmatic children. Conclusions Children with asthma have a higher rate of mental health conditions than non-asthmatic children. Standardized diagnosis and treatment may help reduce the risk of neuropsychiatric conditions. |
| first_indexed | 2024-12-13T17:11:22Z |
| format | Article |
| id | doaj.art-8f0543690edb4a90b2200f3226718a77 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-12-13T17:11:22Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-8f0543690edb4a90b2200f3226718a772022-12-21T23:37:33ZengBMCBMC Pediatrics1471-24312019-11-0119111010.1186/s12887-019-1834-7Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid toolHao Zhou0Zhihe Chen1Weiqing Zhao2Ye Liu3Yuxia Cui4Department of Pediatrics, Guizhou Provincial People’s Hospital, Medical College of Guizhou UniversityDepartment of Pediatrics, Guizhou Provincial People’s Hospital, Medical College of Guizhou UniversityDepartment of Pediatrics, Guizhou Provincial People’s Hospital, Medical College of Guizhou UniversityOtolaryngological Department, Guizhou Provincial People’s Hospital, Medical College of Guizhou UniversityDepartment of Pediatrics, Guizhou Provincial People’s Hospital, Medical College of Guizhou UniversityAbstract Background The mental health and quality of life in children with asthma have attracted widespread attention. This study focused on the evaluation of mental health conditions and their clinical characteristics in Chinese children with asthma. Methods A total of 261 children with asthma aged 6 to 16 years old and 261 age- and gender-matched children from the general population were recruited to participate in this study from Guizhou Provincial People’s Hospital. The parents of all subjects were interviewed using the MINI Kid and were required to finish a clinical characteristics questionnaire. Logistic regression analysis was performed to evaluate risk factors. Results The prevalence of mental health conditions in the asthma group was significantly higher than that in the control group (26.4% vs 14.6%, P < 0.001). A total of 10 mental health conditions was identified in the asthma group, the most common of which was ADHD (11.5%; 30/261), followed by oppositional defiant disorder (ODD) (10.7%; 28/261), separation anxiety disorder (6.1%; 16/261), social anxiety disorder (3.8%; 10/261), specific phobias (2.3%; 6/261), agoraphobia without panic (1.5%; 4/261), (mild) manic episodes (1.1%; 3/261), major depressive episodes (MDEs) (0.8%; 2/261), movement (tic) disorder (0.8%; 2/261), and dysthymia (0.4%; 1/261). A total of 6 neuropsychiatric conditions was detected in the control group, including ODD (5.7%; 15/261), ADHD (4.6%; 12/261), social anxiety disorder (3.1%; 8/261), seasonal anxiety disorder (SAD) (2.3%; 6/261), specific phobias (1.1%; 3/261), and agoraphobia without panic (0.4%; 1/261). The prevalence rates of ODD, ADHD, and SAD differed significantly between the two groups (P < 0.05). Multiple regression analysis revealed that severe persistent asthma (OR = 3.077, 95% CI 1.286–7.361), poor asthma control (OR = 2.005, 95% CI 1.111–3.619), and having asthma for > 3 years (OR = 2.948, 95% CI 1.580–5.502) were independent risk factors for the presence of mental health conditions in asthmatic children. Conclusions Children with asthma have a higher rate of mental health conditions than non-asthmatic children. Standardized diagnosis and treatment may help reduce the risk of neuropsychiatric conditions.http://link.springer.com/article/10.1186/s12887-019-1834-7AsthmaComorbidityRisk factorsChildren |
| spellingShingle | Hao Zhou Zhihe Chen Weiqing Zhao Ye Liu Yuxia Cui Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool BMC Pediatrics Asthma Comorbidity Risk factors Children |
| title | Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool |
| title_full | Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool |
| title_fullStr | Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool |
| title_full_unstemmed | Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool |
| title_short | Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool |
| title_sort | evaluation of neuropsychiatric comorbidities and their clinical characteristics in chinese children with asthma using the mini kid tool |
| topic | Asthma Comorbidity Risk factors Children |
| url | http://link.springer.com/article/10.1186/s12887-019-1834-7 |
| work_keys_str_mv | AT haozhou evaluationofneuropsychiatriccomorbiditiesandtheirclinicalcharacteristicsinchinesechildrenwithasthmausingtheminikidtool AT zhihechen evaluationofneuropsychiatriccomorbiditiesandtheirclinicalcharacteristicsinchinesechildrenwithasthmausingtheminikidtool AT weiqingzhao evaluationofneuropsychiatriccomorbiditiesandtheirclinicalcharacteristicsinchinesechildrenwithasthmausingtheminikidtool AT yeliu evaluationofneuropsychiatriccomorbiditiesandtheirclinicalcharacteristicsinchinesechildrenwithasthmausingtheminikidtool AT yuxiacui evaluationofneuropsychiatriccomorbiditiesandtheirclinicalcharacteristicsinchinesechildrenwithasthmausingtheminikidtool |