Anti-factor H antibody and its role in atypical hemolytic uremic syndrome

Anti-factor H antibody and its role in atypical hemolytic uremic syndrome

Atypical hemolytic uremic syndrome (aHUS) an important form of a thrombotic microangiopathy (TMA) that can frequently lead to acute kidney injury (AKI). An important subset of aHUS is the anti-factor H associated aHUS. This variant of aHUS can occur due to deletion of the complement factor H genes,...

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Bibliographic Details
Main Authors: Rupesh Raina, Guneive Mangat, Gordon Hong, Raghav Shah, Nikhil Nair, Brian Abboud, Sumedha Bagga, Sidharth Kumar Sethi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
anti-factor H antibody
atypical hemolytic uremic syndrome
aHUS
pediatric
factor H
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.931210/full

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