Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report
Eva Krishna Sutedja, Ghabrina Saraswati Elgianda, Endang Sutedja, Kartika Ruchiatan Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, IndonesiaCorrespondence: Eva Krishna Sutedja, Department of Dermatology and Venereology, F...
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| Language: | English |
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Dove Medical Press
2023-06-01
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| Series: | International Medical Case Reports Journal |
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| Online Access: | https://www.dovepress.com/superficial-basal-cell-carcinoma-on-the-back-region-treated-with-a-com-peer-reviewed-fulltext-article-IMCRJ |
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| author | Sutedja EK Elgianda GS Sutedja E Ruchiatan K |
| author_facet | Sutedja EK Elgianda GS Sutedja E Ruchiatan K |
| author_sort | Sutedja EK |
| collection | DOAJ |
| description | Eva Krishna Sutedja, Ghabrina Saraswati Elgianda, Endang Sutedja, Kartika Ruchiatan Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, IndonesiaCorrespondence: Eva Krishna Sutedja, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur No. 38, Bandung, West Java, 40161, Indonesia, Tel +62222032426 ext. 3449, Fax +62222032426, Email evakrishna@yahoo.comAbstract: Basal cell carcinoma (BCC) is the most common skin malignancy, consisting of cells in the basal layer epidermis and its appendix. Superficial BCC is the second most common BCC subtype with a predilection on the trunk including the waist and can be treated with cryoimmunotherapy, a combination of cryotherapy and imiquimod cream. Herein, we report a case of superficial BCC in a 60-year-old woman which was triggered by short-wave diathermic (SWD) therapy on the waist one year previously. Superficial BCC was diagnosed based on clinical symptoms, a dermoscopy, and histopathology. The erythematous and hyperpigmented plaque on the waist had well-defined edges and bled easily. There were pseudopods, a blue-grey ovoid nest, haemorrhagic ulceration, and a deeply pigmented border with basaloid cells in the basal layer of the epidermis and palisade cells at the edges. The patient was treated with cryoimmunotherapy consisting of two cycles of a 30-second freeze time and a 5 mm margin, then two weeks later, 5% imiquimod cream was applied to the skin for five consecutive nights, followed by two days off for six cycles (six weeks). Follow-up at three months revealed clinical improvement with reduced lesion size, confirming that cryoimmunotherapy is an effective treatment for the management of superficial BCC with mild side effects.Keywords: cryoimmunotherapy, superficial basal cell carcinoma, therapy |
| first_indexed | 2024-03-13T01:48:36Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-03-13T01:48:36Z |
| publishDate | 2023-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-8f164edd3154439999915e359cd6652b2023-07-02T19:49:20ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2023-06-01Volume 1639139684718Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case ReportSutedja EKElgianda GSSutedja ERuchiatan KEva Krishna Sutedja, Ghabrina Saraswati Elgianda, Endang Sutedja, Kartika Ruchiatan Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, IndonesiaCorrespondence: Eva Krishna Sutedja, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur No. 38, Bandung, West Java, 40161, Indonesia, Tel +62222032426 ext. 3449, Fax +62222032426, Email evakrishna@yahoo.comAbstract: Basal cell carcinoma (BCC) is the most common skin malignancy, consisting of cells in the basal layer epidermis and its appendix. Superficial BCC is the second most common BCC subtype with a predilection on the trunk including the waist and can be treated with cryoimmunotherapy, a combination of cryotherapy and imiquimod cream. Herein, we report a case of superficial BCC in a 60-year-old woman which was triggered by short-wave diathermic (SWD) therapy on the waist one year previously. Superficial BCC was diagnosed based on clinical symptoms, a dermoscopy, and histopathology. The erythematous and hyperpigmented plaque on the waist had well-defined edges and bled easily. There were pseudopods, a blue-grey ovoid nest, haemorrhagic ulceration, and a deeply pigmented border with basaloid cells in the basal layer of the epidermis and palisade cells at the edges. The patient was treated with cryoimmunotherapy consisting of two cycles of a 30-second freeze time and a 5 mm margin, then two weeks later, 5% imiquimod cream was applied to the skin for five consecutive nights, followed by two days off for six cycles (six weeks). Follow-up at three months revealed clinical improvement with reduced lesion size, confirming that cryoimmunotherapy is an effective treatment for the management of superficial BCC with mild side effects.Keywords: cryoimmunotherapy, superficial basal cell carcinoma, therapyhttps://www.dovepress.com/superficial-basal-cell-carcinoma-on-the-back-region-treated-with-a-com-peer-reviewed-fulltext-article-IMCRJcryoimmunotherapysuperficial basal cell carcinomatherapy |
| spellingShingle | Sutedja EK Elgianda GS Sutedja E Ruchiatan K Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report International Medical Case Reports Journal cryoimmunotherapy superficial basal cell carcinoma therapy |
| title | Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report |
| title_full | Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report |
| title_fullStr | Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report |
| title_full_unstemmed | Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report |
| title_short | Superficial Basal Cell Carcinoma on the Back Region Treated with a Combination of Cryotherapy and 5% Imiquimod Cream: A Case Report |
| title_sort | superficial basal cell carcinoma on the back region treated with a combination of cryotherapy and 5 imiquimod cream a case report |
| topic | cryoimmunotherapy superficial basal cell carcinoma therapy |
| url | https://www.dovepress.com/superficial-basal-cell-carcinoma-on-the-back-region-treated-with-a-com-peer-reviewed-fulltext-article-IMCRJ |
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