Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
<p>Abstract</p> <p>Background</p> <p>Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people.</p> <...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2003-06-01
|
| Series: | Lipids in Health and Disease |
| Subjects: | |
| Online Access: | http://www.Lipidworld.com/content/2/1/3 |
| _version_ | 1818824095964332032 |
|---|---|
| author | Papaioannou Ioanna Zeimbekis Akis Chrysohoou Christina Panagiotakos Demosthenes B Pitsavos Christos Skoumas John Toutouza Marina Toutouzas Pavlos Stefanadis Christodoulos |
| author_facet | Papaioannou Ioanna Zeimbekis Akis Chrysohoou Christina Panagiotakos Demosthenes B Pitsavos Christos Skoumas John Toutouza Marina Toutouzas Pavlos Stefanadis Christodoulos |
| author_sort | Papaioannou Ioanna |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people.</p> <p>Methods</p> <p>The ATTICA study is a population – based cohort that has randomly enrolled 2772 individuals, stratified by age – gender (according to the census 2001), from the greater area of Athens, during 2001–2002. Of them, 1376 were men (45 ± 12 years old, range: 18 – 86) and 1396 women (45 ± 13 years old, range: 18 – 88). We assessed the relationship between physical activity status (measured in kcal/min expended per day) and several lipids, after taking into account the effect of several characteristics of the participants.</p> <p>Results</p> <p>578 (42%) men and 584 (40%) women were classified as physically active. Compared to sedentary physically active women had significantly lower levels of total serum cholesterol (p < 0.05), LDL (p < 0.05) and oxidized LDL cholesterol (p < 0.05), triglycerides (p < 0.05), apolipoprotein B (p < 0.05), and higher levels of HDL cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05). Similar associations were observed in men, but the benefits did not reach statistical significance. However, when we adjusted for age, smoking habits and body mass index, physical activity was only significantly associated with higher HDL-cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05) levels, in women, but not in men.</p> <p>Conclusions</p> <p>Substantial independent increases in HDL-cholesterol and apolipoprotein A1 concentrations were observed in women, but not in men, in a Mediterranean cohort.</p> |
| first_indexed | 2024-12-18T23:50:26Z |
| format | Article |
| id | doaj.art-8f1838bf280843508447626a4cbaed01 |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-12-18T23:50:26Z |
| publishDate | 2003-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-8f1838bf280843508447626a4cbaed012022-12-21T20:46:59ZengBMCLipids in Health and Disease1476-511X2003-06-0121310.1186/1476-511X-2-3Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA studyPapaioannou IoannaZeimbekis AkisChrysohoou ChristinaPanagiotakos Demosthenes BPitsavos ChristosSkoumas JohnToutouza MarinaToutouzas PavlosStefanadis Christodoulos<p>Abstract</p> <p>Background</p> <p>Physical activity has long been associated with reduced risk of coronary heart disease (CHD). In this work we evaluated the effect of physical activity on lipid levels, in a sample of cardiovascular disease free people.</p> <p>Methods</p> <p>The ATTICA study is a population – based cohort that has randomly enrolled 2772 individuals, stratified by age – gender (according to the census 2001), from the greater area of Athens, during 2001–2002. Of them, 1376 were men (45 ± 12 years old, range: 18 – 86) and 1396 women (45 ± 13 years old, range: 18 – 88). We assessed the relationship between physical activity status (measured in kcal/min expended per day) and several lipids, after taking into account the effect of several characteristics of the participants.</p> <p>Results</p> <p>578 (42%) men and 584 (40%) women were classified as physically active. Compared to sedentary physically active women had significantly lower levels of total serum cholesterol (p < 0.05), LDL (p < 0.05) and oxidized LDL cholesterol (p < 0.05), triglycerides (p < 0.05), apolipoprotein B (p < 0.05), and higher levels of HDL cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05). Similar associations were observed in men, but the benefits did not reach statistical significance. However, when we adjusted for age, smoking habits and body mass index, physical activity was only significantly associated with higher HDL-cholesterol (p < 0.05) and apolipoprotein A1 (p < 0.05) levels, in women, but not in men.</p> <p>Conclusions</p> <p>Substantial independent increases in HDL-cholesterol and apolipoprotein A1 concentrations were observed in women, but not in men, in a Mediterranean cohort.</p>http://www.Lipidworld.com/content/2/1/3Physical activitylipidsatherosclerosis |
| spellingShingle | Papaioannou Ioanna Zeimbekis Akis Chrysohoou Christina Panagiotakos Demosthenes B Pitsavos Christos Skoumas John Toutouza Marina Toutouzas Pavlos Stefanadis Christodoulos Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study Lipids in Health and Disease Physical activity lipids atherosclerosis |
| title | Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study |
| title_full | Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study |
| title_fullStr | Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study |
| title_full_unstemmed | Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study |
| title_short | Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study |
| title_sort | physical activity high density lipoprotein cholesterol and other lipids levels in men and women from the attica study |
| topic | Physical activity lipids atherosclerosis |
| url | http://www.Lipidworld.com/content/2/1/3 |
| work_keys_str_mv | AT papaioannouioanna physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT zeimbekisakis physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT chrysohoouchristina physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT panagiotakosdemosthenesb physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT pitsavoschristos physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT skoumasjohn physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT toutouzamarina physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT toutouzaspavlos physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy AT stefanadischristodoulos physicalactivityhighdensitylipoproteincholesterolandotherlipidslevelsinmenandwomenfromtheatticastudy |