Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease
Butyrylcholinesterase (BuChE) and neuroinflammation have recently emerged as promising therapeutic directions for Alzheimer’s disease (AD). Herein, we synthesised 19 novel pyranone-carbamate derivatives and evaluated their activities against cholinesterases and neuroinflammation. The optimal compoun...
| Главные авторы: | , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Taylor & Francis Group
2024-12-01
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| Серии: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Предметы: | |
| Online-ссылка: | https://www.tandfonline.com/doi/10.1080/14756366.2024.2313682 |