Fatty Acid Synthesis in Glial Cells of the CNS
Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/15/8159 |
| _version_ | 1797525527116906496 |
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| author | Aida V. Garcia Corrales Mansour Haidar Jeroen F. J. Bogie Jerome J. A. Hendriks |
| author_facet | Aida V. Garcia Corrales Mansour Haidar Jeroen F. J. Bogie Jerome J. A. Hendriks |
| author_sort | Aida V. Garcia Corrales |
| collection | DOAJ |
| description | Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer’s disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases. |
| first_indexed | 2024-03-10T09:14:13Z |
| format | Article |
| id | doaj.art-8f1cb37cf48a4314b7b7864d8f9cc8cf |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T09:14:13Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-8f1cb37cf48a4314b7b7864d8f9cc8cf2023-11-22T05:44:14ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-07-012215815910.3390/ijms22158159Fatty Acid Synthesis in Glial Cells of the CNSAida V. Garcia Corrales0Mansour Haidar1Jeroen F. J. Bogie2Jerome J. A. Hendriks3Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, BelgiumDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, BelgiumDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, BelgiumDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, BelgiumFatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer’s disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.https://www.mdpi.com/1422-0067/22/15/8159fatty acidsgliacentral nervous systemneurological diseaseCNS repair |
| spellingShingle | Aida V. Garcia Corrales Mansour Haidar Jeroen F. J. Bogie Jerome J. A. Hendriks Fatty Acid Synthesis in Glial Cells of the CNS International Journal of Molecular Sciences fatty acids glia central nervous system neurological disease CNS repair |
| title | Fatty Acid Synthesis in Glial Cells of the CNS |
| title_full | Fatty Acid Synthesis in Glial Cells of the CNS |
| title_fullStr | Fatty Acid Synthesis in Glial Cells of the CNS |
| title_full_unstemmed | Fatty Acid Synthesis in Glial Cells of the CNS |
| title_short | Fatty Acid Synthesis in Glial Cells of the CNS |
| title_sort | fatty acid synthesis in glial cells of the cns |
| topic | fatty acids glia central nervous system neurological disease CNS repair |
| url | https://www.mdpi.com/1422-0067/22/15/8159 |
| work_keys_str_mv | AT aidavgarciacorrales fattyacidsynthesisinglialcellsofthecns AT mansourhaidar fattyacidsynthesisinglialcellsofthecns AT jeroenfjbogie fattyacidsynthesisinglialcellsofthecns AT jeromejahendriks fattyacidsynthesisinglialcellsofthecns |