An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients
Introduction Since coronavirus disease 2019 (COVID-19) has limited treatment options, concern has been raised over secondary infections and antimicrobial resistance (AMR) patterns. It has been observed that patients who were infected with COVID-19 were predisposed to develop secondary infections. Th...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-09-01
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| Series: | Journal of Laboratory Physicians |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1741438 |
| _version_ | 1811183608176574464 |
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| author | Sushma Yadav Boorgula Sadhana Yelamanchili Pragathi Kottapalli Mohini D. Naga |
| author_facet | Sushma Yadav Boorgula Sadhana Yelamanchili Pragathi Kottapalli Mohini D. Naga |
| author_sort | Sushma Yadav Boorgula |
| collection | DOAJ |
| description | Introduction Since coronavirus disease 2019 (COVID-19) has limited treatment options, concern has been raised over secondary infections and antimicrobial resistance (AMR) patterns. It has been observed that patients who were infected with COVID-19 were predisposed to develop secondary infections. The purpose of the study is to ascertain the prevalence of the bacterial and fungal coinfections in COVID-19 patients, and also to assess the AMR patterns in the obtained isolates.
Methods We have studied 200 clinical samples obtained from 122 COVID-19 positive patients. Pathogens were identified using Vitek 2 system. The demographic and clinical patterns were also observed.
Results A total of 122 patients developed secondary infections. Patients aged more than 40 years were majorly affected (p-value < 0.0001). Respiratory samples (n = 96) were predominant. Klebsiella pneumoniae (n = 68) was the most common pathogen isolated followed by Acinetobacter baumannii (n = 54) and an overall 6% rise in the Carbapenem resistance was observed in the isolates.
Conclusion To contain the secondary infections in COVID-19 patients, it is imperative to adhere to antimicrobial stewardship program and timely revise the empirical antibiotic policy. |
| first_indexed | 2024-04-11T09:49:50Z |
| format | Article |
| id | doaj.art-8f1d6121cc6b493b85673ea9f4f4355a |
| institution | Directory Open Access Journal |
| issn | 0974-2727 0974-7826 |
| language | English |
| last_indexed | 2024-04-11T09:49:50Z |
| publishDate | 2022-09-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Laboratory Physicians |
| spelling | doaj.art-8f1d6121cc6b493b85673ea9f4f4355a2022-12-22T04:30:51ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262022-09-01140326026410.1055/s-0041-1741438An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed PatientsSushma Yadav Boorgula0Sadhana Yelamanchili1Pragathi Kottapalli2Mohini D. Naga3Department of Microbiology, AIG Hospitals, Hyderabad, Telangana, IndiaDepartment of Microbiology, AIG Hospitals, Hyderabad, Telangana, IndiaDepartment of Microbiology, AIG Hospitals, Hyderabad, Telangana, IndiaDepartment of Microbiology, AIG Hospitals, Hyderabad, Telangana, IndiaIntroduction Since coronavirus disease 2019 (COVID-19) has limited treatment options, concern has been raised over secondary infections and antimicrobial resistance (AMR) patterns. It has been observed that patients who were infected with COVID-19 were predisposed to develop secondary infections. The purpose of the study is to ascertain the prevalence of the bacterial and fungal coinfections in COVID-19 patients, and also to assess the AMR patterns in the obtained isolates. Methods We have studied 200 clinical samples obtained from 122 COVID-19 positive patients. Pathogens were identified using Vitek 2 system. The demographic and clinical patterns were also observed. Results A total of 122 patients developed secondary infections. Patients aged more than 40 years were majorly affected (p-value < 0.0001). Respiratory samples (n = 96) were predominant. Klebsiella pneumoniae (n = 68) was the most common pathogen isolated followed by Acinetobacter baumannii (n = 54) and an overall 6% rise in the Carbapenem resistance was observed in the isolates. Conclusion To contain the secondary infections in COVID-19 patients, it is imperative to adhere to antimicrobial stewardship program and timely revise the empirical antibiotic policy.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1741438antimicrobial resistancecoagulase-negative staphylococcuscentral line associated bloodstream infections |
| spellingShingle | Sushma Yadav Boorgula Sadhana Yelamanchili Pragathi Kottapalli Mohini D. Naga An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients Journal of Laboratory Physicians antimicrobial resistance coagulase-negative staphylococcus central line associated bloodstream infections |
| title | An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients |
| title_full | An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients |
| title_fullStr | An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients |
| title_full_unstemmed | An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients |
| title_short | An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients |
| title_sort | update on secondary bacterial and fungal infections and their antimicrobial resistance pattern amr in covid 19 confirmed patients |
| topic | antimicrobial resistance coagulase-negative staphylococcus central line associated bloodstream infections |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1741438 |
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