Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies

SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD) along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, d...

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Main Authors: Matthew Lozier, Reina Maria Turcios-Ruiz, Gary Noonan, Pedro Ordunez
Format: Article
Language:English
Published: Pan American Health Organization
Series:Revista Panamericana de Salud Pública
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016001100294&lng=en&tlng=en
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author Matthew Lozier
Reina Maria Turcios-Ruiz
Gary Noonan
Pedro Ordunez
author_facet Matthew Lozier
Reina Maria Turcios-Ruiz
Gary Noonan
Pedro Ordunez
author_sort Matthew Lozier
collection DOAJ
description SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD) along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT). According to the Pan American Health Organization (PAHO) mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC), and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age < 60 years with CKD, without type 1 diabetes mellitus, hypertensive diseases, and other well-known causes of CKD. A probable case of CKDnT is defined as a suspect case with the same findings confirmed three or more months later.
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spelling doaj.art-8f1dee29e9314a4c99ecf121af3c35672022-12-22T02:58:42ZengPan American Health OrganizationRevista Panamericana de Salud Pública1680-5348405294300S1020-49892016001100294Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studiesMatthew LozierReina Maria Turcios-RuizGary NoonanPedro OrdunezSYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD) along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT). According to the Pan American Health Organization (PAHO) mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC), and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age < 60 years with CKD, without type 1 diabetes mellitus, hypertensive diseases, and other well-known causes of CKD. A probable case of CKDnT is defined as a suspect case with the same findings confirmed three or more months later.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016001100294&lng=en&tlng=enInsuficiencia renal crónicaenfermedades renalesnefritisenfermedad crónicavigilancia epidemiológicadiagnóstico diferencialAmérica Central
spellingShingle Matthew Lozier
Reina Maria Turcios-Ruiz
Gary Noonan
Pedro Ordunez
Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
Revista Panamericana de Salud Pública
Insuficiencia renal crónica
enfermedades renales
nefritis
enfermedad crónica
vigilancia epidemiológica
diagnóstico diferencial
América Central
title Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
title_full Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
title_fullStr Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
title_full_unstemmed Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
title_short Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies
title_sort chronic kidney disease of nontraditional etiology in central america a provisional epidemiologic case definition for surveillance and epidemiologic studies
topic Insuficiencia renal crónica
enfermedades renales
nefritis
enfermedad crónica
vigilancia epidemiológica
diagnóstico diferencial
América Central
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016001100294&lng=en&tlng=en
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