Prosthetic heart valves for transcatheter aortic valve replacement
Abstract Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster postoperative recovery, which has brought the possibility to the elderly patient with valvular heart disease and is gradually replacing surgical aortic valve replacement (SAVR). The interventional val...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-06-01
|
| Series: | BMEMat |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/bmm2.12026 |
| _version_ | 1797215300012212224 |
|---|---|
| author | Xinman Hu Shifen Li Pai Peng Beiduo Wang Wenxing Liu Xiaofei Dong Xiayan Yang Miroslav Karabaliev Qifeng Yu Changyou Gao |
| author_facet | Xinman Hu Shifen Li Pai Peng Beiduo Wang Wenxing Liu Xiaofei Dong Xiayan Yang Miroslav Karabaliev Qifeng Yu Changyou Gao |
| author_sort | Xinman Hu |
| collection | DOAJ |
| description | Abstract Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster postoperative recovery, which has brought the possibility to the elderly patient with valvular heart disease and is gradually replacing surgical aortic valve replacement (SAVR). The interventional valve used in TAVR needs to be compressed and transported through the catheter to the lesion site, and can still recover its original shape, structure and performance. This process requires that the material should be flexible, and the rigid mechanical valves in SAVR are not suitable. Recently, decellularized biological valves have been widely used in clinical practice, but their poor durability causes a limitation for long‐term implantation. Therefore, the anti‐calcification modification of biological valves and the design of new polymeric valves with good biostability have gained considerable attention. This review summarizes the calcification mechanism of biological valves and the research progress in anti‐calcification modification strategies. Besides, the development of new polymeric valves is included, with special attention to representative cases, such as polysiloxane, polytetrafluorethylene, poly(styrene‐block‐isobutylene‐block‐styrene), and polyurethane‐based materials. Finally, the challenges and future perspectives of artificial heart valve materials are discussed. |
| first_indexed | 2024-03-13T00:33:05Z |
| format | Article |
| id | doaj.art-8f218e67ce3548db93443b115b2b5032 |
| institution | Directory Open Access Journal |
| issn | 2751-7446 |
| language | English |
| last_indexed | 2024-04-24T11:27:52Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | BMEMat |
| spelling | doaj.art-8f218e67ce3548db93443b115b2b50322024-04-10T13:21:01ZengWileyBMEMat2751-74462023-06-0112n/an/a10.1002/bmm2.12026Prosthetic heart valves for transcatheter aortic valve replacementXinman Hu0Shifen Li1Pai Peng2Beiduo Wang3Wenxing Liu4Xiaofei Dong5Xiayan Yang6Miroslav Karabaliev7Qifeng Yu8Changyou Gao9MOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaShanghai NewMed Medical Technology Co., Ltd Shanghai ChinaDepartment of Medical Physics, Biophysics and Radiology Faculty of Medicine Trakia University Stara Zagora BulgariaShanghai NewMed Medical Technology Co., Ltd Shanghai ChinaMOE Key Laboratory of Macromolecular Synthesis and Functionalization International Research Center for Functional Polymers Department of Polymer Science and Engineering Zhejiang University Hangzhou ChinaAbstract Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster postoperative recovery, which has brought the possibility to the elderly patient with valvular heart disease and is gradually replacing surgical aortic valve replacement (SAVR). The interventional valve used in TAVR needs to be compressed and transported through the catheter to the lesion site, and can still recover its original shape, structure and performance. This process requires that the material should be flexible, and the rigid mechanical valves in SAVR are not suitable. Recently, decellularized biological valves have been widely used in clinical practice, but their poor durability causes a limitation for long‐term implantation. Therefore, the anti‐calcification modification of biological valves and the design of new polymeric valves with good biostability have gained considerable attention. This review summarizes the calcification mechanism of biological valves and the research progress in anti‐calcification modification strategies. Besides, the development of new polymeric valves is included, with special attention to representative cases, such as polysiloxane, polytetrafluorethylene, poly(styrene‐block‐isobutylene‐block‐styrene), and polyurethane‐based materials. Finally, the challenges and future perspectives of artificial heart valve materials are discussed.https://doi.org/10.1002/bmm2.12026biological valvecalcificationdurabilitypolymeric valvetranscatheter aortic valve replacement (TAVR) |
| spellingShingle | Xinman Hu Shifen Li Pai Peng Beiduo Wang Wenxing Liu Xiaofei Dong Xiayan Yang Miroslav Karabaliev Qifeng Yu Changyou Gao Prosthetic heart valves for transcatheter aortic valve replacement BMEMat biological valve calcification durability polymeric valve transcatheter aortic valve replacement (TAVR) |
| title | Prosthetic heart valves for transcatheter aortic valve replacement |
| title_full | Prosthetic heart valves for transcatheter aortic valve replacement |
| title_fullStr | Prosthetic heart valves for transcatheter aortic valve replacement |
| title_full_unstemmed | Prosthetic heart valves for transcatheter aortic valve replacement |
| title_short | Prosthetic heart valves for transcatheter aortic valve replacement |
| title_sort | prosthetic heart valves for transcatheter aortic valve replacement |
| topic | biological valve calcification durability polymeric valve transcatheter aortic valve replacement (TAVR) |
| url | https://doi.org/10.1002/bmm2.12026 |
| work_keys_str_mv | AT xinmanhu prostheticheartvalvesfortranscatheteraorticvalvereplacement AT shifenli prostheticheartvalvesfortranscatheteraorticvalvereplacement AT paipeng prostheticheartvalvesfortranscatheteraorticvalvereplacement AT beiduowang prostheticheartvalvesfortranscatheteraorticvalvereplacement AT wenxingliu prostheticheartvalvesfortranscatheteraorticvalvereplacement AT xiaofeidong prostheticheartvalvesfortranscatheteraorticvalvereplacement AT xiayanyang prostheticheartvalvesfortranscatheteraorticvalvereplacement AT miroslavkarabaliev prostheticheartvalvesfortranscatheteraorticvalvereplacement AT qifengyu prostheticheartvalvesfortranscatheteraorticvalvereplacement AT changyougao prostheticheartvalvesfortranscatheteraorticvalvereplacement |