Oxidative Stress in Multiple Sclerosis Disease (Review Article)

Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, in which the myelin sheaths got injured. The prevalence of MS is on grow, as well as, it affects the young ages. Females are most common to have MS compared to males. Oxidative stress is the situation of i...

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Bibliographic Details
Main Authors: Sura Mohammed Kadhim, Sura Mohsin Abbood, Yasser Mohammed Taay, Mustafa Taha Mohammed
Format: Article
Language:English
Published: College of medicine/ University of Diyala 2021-12-01
Series:Diyala Journal of Medicine
Subjects:
Online Access:http://djm.uodiyala.edu.iq/index.php/djm/article/view/858
Description
Summary:Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, in which the myelin sheaths got injured. The prevalence of MS is on grow, as well as, it affects the young ages. Females are most common to have MS compared to males. Oxidative stress is the situation of imbalance between oxidants (free radicals and reactive oxygen species (ROS)) and antioxidants in a living system, in which either the oxidants are elevated or antioxidants are reduced, or sometimes both. ROS and oxidative stress have been implicated in the progression of many degenerative diseases, which is important in cracking the unrevealed mysteries of MS. In this review article, some of the proposed mechanisms that link oxidative stress with MS disease would be described.
ISSN:2219-9764
2617-8982