Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins
The aim of this work was to investigate selected biological and toxicity properties of cured epoxy resin-based compounds based on a bisphenol A epoxy resin, cold-cured by a polyamide and containing two types of metal powders (aluminum and copper). This study involved cytotoxicity analysis, pH measur...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/22/4915 |
| _version_ | 1797464166802391040 |
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| author | Anna Rudawska Katarzyna Sarna-Boś Adrianna Rudawska Ewa Olewnik-Kruszkowska Mariaenrica Frigione |
| author_facet | Anna Rudawska Katarzyna Sarna-Boś Adrianna Rudawska Ewa Olewnik-Kruszkowska Mariaenrica Frigione |
| author_sort | Anna Rudawska |
| collection | DOAJ |
| description | The aim of this work was to investigate selected biological and toxicity properties of cured epoxy resin-based compounds based on a bisphenol A epoxy resin, cold-cured by a polyamide and containing two types of metal powders (aluminum and copper). This study involved cytotoxicity analysis, pH measurements, absorbance measurements and sterilization. The cytotoxicity analysis was conducted to determine the harmful degree of the cured epoxy resin. Aimed at identifying toxic agents in cured compounds, the cytotoxicity analysis involved absorbance measurements in an entire wavelength range. Cytotoxicity and absorbance results demonstrated that the extracts of all the tested resin samples had no cytotoxic effects on the cells of living organisms. The absorbance values obtained over the entire wavelength range did not point to the formation of aggregations, which proved that no toxic agents harmful to living organisms were extracted from the resin samples. Based on the results obtained, it can be concluded that all tested compounds, based on epoxy resins, which are also used as adhesives in various applications, are essentially safe materials when using such formulations in a cured state. |
| first_indexed | 2024-03-09T18:03:08Z |
| format | Article |
| id | doaj.art-8f27822991714f1db3650ba144ae995b |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T18:03:08Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-8f27822991714f1db3650ba144ae995b2023-11-24T09:43:05ZengMDPI AGPolymers2073-43602022-11-011422491510.3390/polym14224915Biological Effects and Toxicity of Compounds Based on Cured Epoxy ResinsAnna Rudawska0Katarzyna Sarna-Boś1Adrianna Rudawska2Ewa Olewnik-Kruszkowska3Mariaenrica Frigione4Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36 St., 20-618 Lublin, PolandDepartment of Dental Prosthetics, Medical University of Lublin, Chodźki 6, 20-093 Lublin, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Aleja Partyzantów 57, 24-100 Puławy, PolandFaculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7 St., 87-200 Toruń, PolandDepartment of Innovation Engineering, University of Salento, Via Arnesano, 73100 Lecce, ItalyThe aim of this work was to investigate selected biological and toxicity properties of cured epoxy resin-based compounds based on a bisphenol A epoxy resin, cold-cured by a polyamide and containing two types of metal powders (aluminum and copper). This study involved cytotoxicity analysis, pH measurements, absorbance measurements and sterilization. The cytotoxicity analysis was conducted to determine the harmful degree of the cured epoxy resin. Aimed at identifying toxic agents in cured compounds, the cytotoxicity analysis involved absorbance measurements in an entire wavelength range. Cytotoxicity and absorbance results demonstrated that the extracts of all the tested resin samples had no cytotoxic effects on the cells of living organisms. The absorbance values obtained over the entire wavelength range did not point to the formation of aggregations, which proved that no toxic agents harmful to living organisms were extracted from the resin samples. Based on the results obtained, it can be concluded that all tested compounds, based on epoxy resins, which are also used as adhesives in various applications, are essentially safe materials when using such formulations in a cured state.https://www.mdpi.com/2073-4360/14/22/4915epoxidesresin-based compositesbiological effectcytotoxic effectmetallic fillers |
| spellingShingle | Anna Rudawska Katarzyna Sarna-Boś Adrianna Rudawska Ewa Olewnik-Kruszkowska Mariaenrica Frigione Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins Polymers epoxides resin-based composites biological effect cytotoxic effect metallic fillers |
| title | Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins |
| title_full | Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins |
| title_fullStr | Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins |
| title_full_unstemmed | Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins |
| title_short | Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins |
| title_sort | biological effects and toxicity of compounds based on cured epoxy resins |
| topic | epoxides resin-based composites biological effect cytotoxic effect metallic fillers |
| url | https://www.mdpi.com/2073-4360/14/22/4915 |
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