HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test
In order to reduce the window phase between time of human immunodeficiency virus (HIV) exposure and source’s results of laboratory investigations, we evaluated the analytical performance of a new point of care test for simultaneous detection of HIV Abs and HIV Ag.We tested 48 serum samples by HIV Co...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2010-12-01
|
| Series: | Microbiologia Medica |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/mm/article/view/2412 |
| _version_ | 1818532248424546304 |
|---|---|
| author | Marta Monari Serenella Valaperta Eleonora Baldassarre Roberto Assandri Alessandro Montanelli |
| author_facet | Marta Monari Serenella Valaperta Eleonora Baldassarre Roberto Assandri Alessandro Montanelli |
| author_sort | Marta Monari |
| collection | DOAJ |
| description | In order to reduce the window phase between time of human immunodeficiency virus (HIV) exposure and source’s results of laboratory investigations, we evaluated the analytical performance of a new point of care test for simultaneous detection of HIV Abs and HIV Ag.We tested 48 serum samples by HIV Combo Ag/Ab Abbott Diagnostic®, USA; by Western Blot Matrix HIV 1/2 Abbott®, USA and by the new POCT test HIV 1/2 Ag/Ab Combo Inverness Medical®, UK. Good concordance of results was recordered with analytical performance (sensitivity and specificity) and diagnostic accuracy of 100%.Thus this new test is ideal for rapid laboratory investigation when the time for appropriate prophylactic therapy is very important, such as found in exposure in the workplace. |
| first_indexed | 2024-12-11T17:43:01Z |
| format | Article |
| id | doaj.art-8f27b21030b9405c93858d76a149caef |
| institution | Directory Open Access Journal |
| issn | 2280-6423 |
| language | English |
| last_indexed | 2024-12-11T17:43:01Z |
| publishDate | 2010-12-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Microbiologia Medica |
| spelling | doaj.art-8f27b21030b9405c93858d76a149caef2022-12-22T00:56:28ZengPAGEPress PublicationsMicrobiologia Medica2280-64232010-12-0125410.4081/mm.2010.24121667HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care testMarta MonariSerenella ValapertaEleonora BaldassarreRoberto AssandriAlessandro MontanelliIn order to reduce the window phase between time of human immunodeficiency virus (HIV) exposure and source’s results of laboratory investigations, we evaluated the analytical performance of a new point of care test for simultaneous detection of HIV Abs and HIV Ag.We tested 48 serum samples by HIV Combo Ag/Ab Abbott Diagnostic®, USA; by Western Blot Matrix HIV 1/2 Abbott®, USA and by the new POCT test HIV 1/2 Ag/Ab Combo Inverness Medical®, UK. Good concordance of results was recordered with analytical performance (sensitivity and specificity) and diagnostic accuracy of 100%.Thus this new test is ideal for rapid laboratory investigation when the time for appropriate prophylactic therapy is very important, such as found in exposure in the workplace.http://www.pagepressjournals.org/index.php/mm/article/view/2412HIV, exposure, POCT |
| spellingShingle | Marta Monari Serenella Valaperta Eleonora Baldassarre Roberto Assandri Alessandro Montanelli HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test Microbiologia Medica HIV, exposure, POCT |
| title | HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test |
| title_full | HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test |
| title_fullStr | HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test |
| title_full_unstemmed | HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test |
| title_short | HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test |
| title_sort | hiv 1 2 ag ab selective and combined detection by a new rapid point of care test |
| topic | HIV, exposure, POCT |
| url | http://www.pagepressjournals.org/index.php/mm/article/view/2412 |
| work_keys_str_mv | AT martamonari hiv12agabselectiveandcombineddetectionbyanewrapidpointofcaretest AT serenellavalaperta hiv12agabselectiveandcombineddetectionbyanewrapidpointofcaretest AT eleonorabaldassarre hiv12agabselectiveandcombineddetectionbyanewrapidpointofcaretest AT robertoassandri hiv12agabselectiveandcombineddetectionbyanewrapidpointofcaretest AT alessandromontanelli hiv12agabselectiveandcombineddetectionbyanewrapidpointofcaretest |