Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study
Background and Aims: Bupivacaine has been the most frequently used local anaesthetic in brachial plexus block, but ropivacaine has also been successfully tried in the recent past. It is less cardiotoxic, less arrhythmogenic, less toxic to the central nervous system than bupivacaine, and it has intri...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Indian Journal of Anaesthesia |
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| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2014;volume=58;issue=6;spage=709;epage=713;aulast=Ali |
| _version_ | 1818855224168677376 |
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| author | Qazi Ehsan Ali L Manjunatha Syed Hussain Amir Shaista Jamil Abdul Quadir |
| author_facet | Qazi Ehsan Ali L Manjunatha Syed Hussain Amir Shaista Jamil Abdul Quadir |
| author_sort | Qazi Ehsan Ali |
| collection | DOAJ |
| description | Background and Aims: Bupivacaine has been the most frequently used local anaesthetic in brachial plexus block, but ropivacaine has also been successfully tried in the recent past. It is less cardiotoxic, less arrhythmogenic, less toxic to the central nervous system than bupivacaine, and it has intrinsic vasoconstrictor property. The effects of clonidine have been studied in peripheral nerve blockade. The purpose of this study was to evaluate the effects of clonidine on nerve blockade during brachial plexus block with ropivacaine using peripheral nerve stimulator. Methods: Sixty patients were randomly divided into two groups, Group A and B. Group A received 30 ml of 0.5% of ropivacaine with 0.5 ml normal saline while Group B received same amount of ropivacaine with 0.5 ml (equivalent to 75 μg) of clonidine for supraclavicular brachial plexus block. The groups were compared regarding quality of sensory and motor blockade, duration of post-operative analgesia and intra and post-operative complications. Results: There was a significant increase in duration of motor and sensory block and analgesia in Group B as compared to Group A patients (P < 0.0001). There was no significant difference in onset time in either group (P = 0.304). No significant side effects were noted. Conclusion: The addition of 75 μg of clonidine to ropivacaine for brachial plexus block prolongs motor and sensory block and analgesia without significant side effects. |
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| format | Article |
| id | doaj.art-8f297861d08c41a0b867aae7af2a6075 |
| institution | Directory Open Access Journal |
| issn | 0019-5049 |
| language | English |
| last_indexed | 2024-12-19T08:05:12Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-8f297861d08c41a0b867aae7af2a60752022-12-21T20:29:46ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50492014-01-0158670971310.4103/0019-5049.147150Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective studyQazi Ehsan AliL ManjunathaSyed Hussain AmirShaista JamilAbdul QuadirBackground and Aims: Bupivacaine has been the most frequently used local anaesthetic in brachial plexus block, but ropivacaine has also been successfully tried in the recent past. It is less cardiotoxic, less arrhythmogenic, less toxic to the central nervous system than bupivacaine, and it has intrinsic vasoconstrictor property. The effects of clonidine have been studied in peripheral nerve blockade. The purpose of this study was to evaluate the effects of clonidine on nerve blockade during brachial plexus block with ropivacaine using peripheral nerve stimulator. Methods: Sixty patients were randomly divided into two groups, Group A and B. Group A received 30 ml of 0.5% of ropivacaine with 0.5 ml normal saline while Group B received same amount of ropivacaine with 0.5 ml (equivalent to 75 μg) of clonidine for supraclavicular brachial plexus block. The groups were compared regarding quality of sensory and motor blockade, duration of post-operative analgesia and intra and post-operative complications. Results: There was a significant increase in duration of motor and sensory block and analgesia in Group B as compared to Group A patients (P < 0.0001). There was no significant difference in onset time in either group (P = 0.304). No significant side effects were noted. Conclusion: The addition of 75 μg of clonidine to ropivacaine for brachial plexus block prolongs motor and sensory block and analgesia without significant side effects.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2014;volume=58;issue=6;spage=709;epage=713;aulast=AliAdjuvantbrachial plexus anaesthesiaclonidineropivacaine |
| spellingShingle | Qazi Ehsan Ali L Manjunatha Syed Hussain Amir Shaista Jamil Abdul Quadir Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study Indian Journal of Anaesthesia Adjuvant brachial plexus anaesthesia clonidine ropivacaine |
| title | Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study |
| title_full | Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study |
| title_fullStr | Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study |
| title_full_unstemmed | Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study |
| title_short | Efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block: A prospective study |
| title_sort | efficacy of clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block a prospective study |
| topic | Adjuvant brachial plexus anaesthesia clonidine ropivacaine |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2014;volume=58;issue=6;spage=709;epage=713;aulast=Ali |
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