Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation.
The oxidative process of LDL particles generates molecules which are structurally similar to platelet-activating factor (PAF), and some effects of oxidized LDL (oxLDL) have been shown to be dependent on PAF receptor (PAFR) activation. In a previous study, we showed that PAFR is required for upregula...
Main Authors: | Francisco J O Rios, Mariana M Koga, Matheus Ferracini, Sonia Jancar |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3343035?pdf=render |
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