Effects of 6-months' Exercise on Cardiac Function, Structure and Metabolism in Female Hypertensive Rats–The Decisive Role of Lysyl Oxidase and Collagen III

Effects of 6-months' Exercise on Cardiac Function, Structure and Metabolism in Female Hypertensive Rats–The Decisive Role of Lysyl Oxidase and Collagen III

Purpose: According to the current therapeutic guidelines of the WHO physical activity and exercise are recommended as first-line therapy of arterial hypertension. Previous results lead to the conclusion, however, that hearts of spontaneously hypertensive rats (SHR) with established hypertension cann...

Full description

Bibliographic Details
Main Authors:	Rolf Schreckenberg, Anja-Maria Horn, Rui M. da Costa Rebelo, Sakine Simsekyilmaz, Bernd Niemann, Ling Li, Susanne Rohrbach, Klaus-Dieter Schlüter
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-08-01
Series:	Frontiers in Physiology
Subjects:	arterial hypertension aerobic exercise cardiac function lysyl oxidase osteopontin cardiac fibrosis
Online Access:	http://journal.frontiersin.org/article/10.3389/fphys.2017.00556/full

Similar Items

The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins
by: Sylvain D. Vallet, et al.
Published: (2020-12-01)

The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling
by: Cristina Rodríguez, et al.
Published: (2019-11-01)

Human Lysyl Oxidase Over-Expression Enhances Baseline Cardiac Oxidative Stress but Does Not Aggravate ROS Generation or Infarct Size Following Myocardial Ischemia-Reperfusion
by: Laura Valls-Lacalle, et al.
Published: (2021-12-01)

Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes
by: Tatyana Liburkin-Dan, et al.
Published: (2022-09-01)

Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy
by: Philip C. Trackman, et al.
Published: (2022-05-01)

Inhibiting Lysyl Oxidases prevents pathologic cartilage calcification
by: Ilaria Bernabei, et al.
Published: (2024-02-01)

Identification and validation of roles of lysyl oxidases in the predictions of prognosis, chemotherapy and immunotherapy in glioma
by: Qin-Xuan Xia, et al.
Published: (2022-08-01)

Lysyl oxidase-like 3 mRNA expression indicates poor survival from oral squamous cell carcinoma
by: Tzong-Ming Shieh, et al.
Published: (2011-12-01)

Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
by: Gavin Tjin, et al.
Published: (2017-11-01)

Properties of a cryptic lysyl oxidase from haloarchaeon Haloterrigena turkmenica
by: Nikolay B. Pestov, et al.
Published: (2019-04-01)

Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis
by: Yimin Yao, et al.
Published: (2022-05-01)

Lack of association between lysyl oxidase-like 1 polymorphisms and primary open angle glaucoma:a meta-analysis
by: Wen Sun, et al.
Published: (2014-06-01)

Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy
by: Manju L. Subramanian, et al.
Published: (2019-09-01)

The Expression Patterns and Roles of Lysyl Oxidases in Aortic Dissection
by: Xin Yi, et al.
Published: (2021-07-01)

Insights from the in silico structural, functional and phylogenetic characterization of canine lysyl oxidase protein
by: Afnan Saleem, et al.
Published: (2020-06-01)

LYSYL OXIDASE (LOX) – A FUTURE NEW ALLY ON THE STAGE OF THE FIGHT AGAINST CANCER
by: Alexandra Totan, et al.
Published: (2019-09-01)

Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
by: Lara Perryman, et al.
Published: (2022-02-01)

Serum Lysyl Oxidase Levels and Lysyl Oxidase Gene Polymorphism in Ovarian Cancer Patients of Eastern Indian Population
by: Suchitra Kumari, et al.
Published: (2021-12-01)

Inhibition of lysyl oxidase accelerates intervertebral disc degeneration induced by apoptosis of nucleus pulposus cells
by: LI Jianmin, et al.
Published: (2023-10-01)

Lysyl Oxidase Family Proteins: Prospective Therapeutic Targets in Cancer
by: Wei Wang, et al.
Published: (2022-10-01)

Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients
by: Eiman A. Abass, et al.
Published: (2018-05-01)

Lysyl Oxidase Family Enzymes and Their Role in Tumor Progression
by: Tanya Liburkin-Dan, et al.
Published: (2022-06-01)

Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
by: Weiping Lin, et al.
Published: (2020-04-01)

Neonatal exposure to hypoxia induces early arterial stiffening via activation of lysyl oxidases
by: Jochen Steppan, et al.
Published: (2023-04-01)

Corrigendum: Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
by: Weiping Lin, et al.
Published: (2020-10-01)

Lysyl oxidase-dependent extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease
by: Carme Ballester-Servera, et al.
Published: (2023-11-01)

Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis
by: Chun Xing, et al.
Published: (2022-01-01)

Implications of lysyl oxidase-like protein 3 expression in the periodontium of diabetic rats
by: Li HUANG, et al.
Published: (2022-09-01)

Mechanistic insight into lysyl oxidase in vascular remodeling and angiogenesis
by: Zhao-Jun Wang, et al.
Published: (2023-05-01)

Mass Spectrometry-Based Disulfide Mapping of Lysyl Oxidase-like 2
by: Alex A. Meier, et al.
Published: (2022-05-01)

Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia
by: Desiree Kunadt, et al.
Published: (2020-06-01)

Lysyl Oxidases: Orchestrators of Cellular Behavior and ECM Remodeling and Homeostasis
by: Shelly Zaffryar-Eilot, et al.
Published: (2022-09-01)

The potential of magnesium sulfate to change serum lysyl oxidase and nitrite level in patients with atherosclerosis: A double-blind clinical trial study
by: Fariba Azarkish, et al.
Published: (2023-10-01)

Investigation of the Ameliorating Effect of Copper Albumin Complex on Lysyl oxidase in monosodium iodoacetate -Induced Knee Osteoarthritis in Rats
by: Olaa M. Galal, et al.
Published: (2023-03-01)

A 3D–Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase–Like 2
by: Alex A. Meier, et al.
Published: (2022-11-01)

Lysyl Oxidases Expression and Breast Cancer Progression: A Bioinformatic Analysis
by: Sofia Ramos, et al.
Published: (2022-06-01)

Tendon mechanical properties are enhanced via recombinant lysyl oxidase treatment
by: Phong K. Nguyen, et al.
Published: (2022-08-01)

Exploring the Interplay between Polyphenols and Lysyl Oxidase Enzymes for Maintaining Extracellular Matrix Homeostasis
by: Carolina Añazco, et al.
Published: (2023-07-01)

Research progress of lysyl oxidase and ophthalmic diseases
by: Man Yang, et al.
Published: (2020-12-01)

Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer
by: Hung-Yu Lin, et al.
Published: (2020-12-01)