Targeting Endothelial HIF2α/ARNT Expression for Ischemic Heart Disease Therapy
Ischemic heart disease (IHD) is a major cause of mortality and morbidity worldwide, with novel therapeutic strategies urgently needed. Endothelial dysfunction is a hallmark of IHD, contributing to its development and progression. Hypoxia-inducible factors (HIFs) are transcription factors activated i...
Main Authors: | Karim Ullah, Lizhuo Ai, Zainab Humayun, Rongxue Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
|
Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/12/7/995 |
Similar Items
-
Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship
by: A. Katharina Ceranski, et al.
Published: (2023-03-01) -
The Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT/HIF-1β) is Influenced by Hypoxia and Hypoxia-Mimetics
by: Matthias Wolff, et al.
Published: (2013-09-01) -
Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia
by: Fatemeh Sadeghi, et al.
Published: (2020-06-01) -
Regulation of the HIF switch in human endothelial and cancer cells
by: Jakub Slawski, et al.
Published: (2024-06-01) -
THE ROLE OF ENDOTHELIN-1, HIF1α, HIF2α IN RETINAL VEIN OCCLUSION
by: M. V. Budzinskaya, et al.
Published: (2019-02-01)