Engineering a vitamin B12 high-throughput screening system by riboswitch sensor in Sinorhizobium meliloti

Engineering a vitamin B12 high-throughput screening system by riboswitch sensor in Sinorhizobium meliloti

Abstract Background As a very important coenzyme in the cell metabolism, Vitamin B12 (cobalamin, VB12) has been widely used in food and medicine fields. The complete biosynthesis of VB12 requires approximately 30 genes, but overexpression of these genes did not result in expected increase of VB12 pr...

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Bibliographic Details
Main Authors: Yingying Cai, Miaomiao Xia, Huina Dong, Yuan Qian, Tongcun Zhang, Beiwei Zhu, Jinchuan Wu, Dawei Zhang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Biotechnology
Subjects:
Vitamin B12
Cobalamin
Sinorhizobium meliloti
Riboswitch
High-throughputScreening
Online Access:http://link.springer.com/article/10.1186/s12896-018-0441-2

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