Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients
Early diagnosis of liver cancer plays a significant role in reducing its high mortality. In this preliminary study, the feasibility of using serum surface-enhanced Raman spectroscopy (SERS) to identify liver cancer was studied. Serum samples were obtained from liver cancer patients and healthy contr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2022-09-01
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| Series: | Journal of Innovative Optical Health Sciences |
| Subjects: | |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S1793545822500328 |
| _version_ | 1811241074885132288 |
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| author | Qiwen Wang Sen Wang Shengdong Cui Deyuan Yang Zheng Huang Shusen Xie |
| author_facet | Qiwen Wang Sen Wang Shengdong Cui Deyuan Yang Zheng Huang Shusen Xie |
| author_sort | Qiwen Wang |
| collection | DOAJ |
| description | Early diagnosis of liver cancer plays a significant role in reducing its high mortality. In this preliminary study, the feasibility of using serum surface-enhanced Raman spectroscopy (SERS) to identify liver cancer was studied. Serum samples were obtained from liver cancer patients and healthy controls. The differences between the SERS spectra of pre-operation and post-operation of liver cancer patients were also analyzed. The general shape and trend of SERS spectra of health control and liver cancer patients were similar. Multivariate analysis, e.g., PLS-SVM, might be useful for the discrimination of serum SERS spectra of pre-operation and post-operation. |
| first_indexed | 2024-04-12T13:30:04Z |
| format | Article |
| id | doaj.art-8f383b274d46446787d7010aeaf5e0ee |
| institution | Directory Open Access Journal |
| issn | 1793-5458 1793-7205 |
| language | English |
| last_indexed | 2024-04-12T13:30:04Z |
| publishDate | 2022-09-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Innovative Optical Health Sciences |
| spelling | doaj.art-8f383b274d46446787d7010aeaf5e0ee2022-12-22T03:31:12ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052022-09-01150510.1142/S1793545822500328Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patientsQiwen Wang0Sen Wang1Shengdong Cui2Deyuan Yang3Zheng Huang4Shusen Xie5MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaMOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaMOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaMOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaMOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaMOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350007, P. R. ChinaEarly diagnosis of liver cancer plays a significant role in reducing its high mortality. In this preliminary study, the feasibility of using serum surface-enhanced Raman spectroscopy (SERS) to identify liver cancer was studied. Serum samples were obtained from liver cancer patients and healthy controls. The differences between the SERS spectra of pre-operation and post-operation of liver cancer patients were also analyzed. The general shape and trend of SERS spectra of health control and liver cancer patients were similar. Multivariate analysis, e.g., PLS-SVM, might be useful for the discrimination of serum SERS spectra of pre-operation and post-operation.https://www.worldscientific.com/doi/10.1142/S1793545822500328Surface-enhanced Raman spectroscopy (SERS)serumliver cancermultivariate analysis |
| spellingShingle | Qiwen Wang Sen Wang Shengdong Cui Deyuan Yang Zheng Huang Shusen Xie Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients Journal of Innovative Optical Health Sciences Surface-enhanced Raman spectroscopy (SERS) serum liver cancer multivariate analysis |
| title | Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients |
| title_full | Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients |
| title_fullStr | Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients |
| title_full_unstemmed | Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients |
| title_short | Multivariate analysis of serum surface-enhanced Raman spectroscopy of liver cancer patients |
| title_sort | multivariate analysis of serum surface enhanced raman spectroscopy of liver cancer patients |
| topic | Surface-enhanced Raman spectroscopy (SERS) serum liver cancer multivariate analysis |
| url | https://www.worldscientific.com/doi/10.1142/S1793545822500328 |
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