Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.

Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.

Aggregates of hyperphosphorylated tau protein are found in a group of diseases called tauopathies, which includes Alzheimer's disease. The causes and consequences of tau hyperphosphorylation are routinely investigated in laboratory animals. Mice are the models of choice as they are easily amena...

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Bibliographic Details
Main Authors: Franck R Petry, Jérôme Pelletier, Alexis Bretteville, Françoise Morin, Frédéric Calon, Sébastien S Hébert, Robert A Whittington, Emmanuel Planel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094251&type=printable

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