Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial
Abstract Background Gait impairment limiting mobility and restricting activities is common after stroke. Auditory rhythmical cueing (ARC) uses a metronome beat delivered during exercise to train stepping and early work reports gait improvements. This study aimed to establish the feasibility of a ful...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Pilot and Feasibility Studies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40814-022-01193-y |
| _version_ | 1817970605516914688 |
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| author | Lisa Shaw Patricia McCue Philip Brown Christopher Buckley Silvia Del Din Richard Francis Heather Hunter Allen Lambert Sue Lord Christopher I. M. Price Helen Rodgers Lynn Rochester Sarah A. Moore |
| author_facet | Lisa Shaw Patricia McCue Philip Brown Christopher Buckley Silvia Del Din Richard Francis Heather Hunter Allen Lambert Sue Lord Christopher I. M. Price Helen Rodgers Lynn Rochester Sarah A. Moore |
| author_sort | Lisa Shaw |
| collection | DOAJ |
| description | Abstract Background Gait impairment limiting mobility and restricting activities is common after stroke. Auditory rhythmical cueing (ARC) uses a metronome beat delivered during exercise to train stepping and early work reports gait improvements. This study aimed to establish the feasibility of a full scale multicentre randomised controlled trial to evaluate an ARC gait and balance training programme for use by stroke survivors in the home and outdoors. Methods A parallel-group observer-blind pilot randomised controlled trial was conducted. Adults within 2 years of stroke with a gait-related mobility impairment were recruited from four NHS stroke services and randomised to an ARC gait and balance training programme (intervention) or the training programme without ARC (control). Both programmes consisted of 3x30 min sessions per week for 6 weeks undertaken at home/nearby outdoor community. One session per week was supervised and the remainder self-managed. Gait and balance performance assessments were undertaken at baseline, 6 and 10 weeks. Key trial outcomes included recruitment and retention rates, programme adherence, assessment data completeness and safety. Results Between November 2018 and February 2020, 59 participants were randomised (intervention n=30, control n=29), mean recruitment rate 4/month. At baseline, 6 weeks and 10 weeks, research assessments were conducted for 59/59 (100%), 47/59 (80%) and 42/59 (71%) participants, respectively. Missing assessments were largely due to discontinuation of data collection from mid-March 2020 because of the UK COVID-19 pandemic lockdown. The proportion of participants with complete data for each individual performance assessment ranged from 100% at baseline to 68% at 10 weeks. In the intervention group, 433/540 (80%) total programme exercise sessions were undertaken, in the control group, 390/522 (75%). Falls were reported by five participants in the intervention group, six in the control group. Three serious adverse events occurred, all unrelated to the study. Conclusion We believe that a definitive multicentre RCT to evaluate the ARC gait and balance training programme is feasible. Recruitment, programme adherence and safety were all acceptable. Although we consider that the retention rate and assessment data completeness were not sufficient for a future trial, this was largely due to the UK COVID-19 pandemic lockdown. Trial registration ISRCTN, ISRCTN10874601 , Registered on 05/03/2018, |
| first_indexed | 2024-04-13T20:36:07Z |
| format | Article |
| id | doaj.art-8f4153f8ab314f3c9d3add8c15bdd0ec |
| institution | Directory Open Access Journal |
| issn | 2055-5784 |
| language | English |
| last_indexed | 2024-04-13T20:36:07Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Pilot and Feasibility Studies |
| spelling | doaj.art-8f4153f8ab314f3c9d3add8c15bdd0ec2022-12-22T02:31:02ZengBMCPilot and Feasibility Studies2055-57842022-11-018111110.1186/s40814-022-01193-yAuditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trialLisa Shaw0Patricia McCue1Philip Brown2Christopher Buckley3Silvia Del Din4Richard Francis5Heather Hunter6Allen Lambert7Sue Lord8Christopher I. M. Price9Helen Rodgers10Lynn Rochester11Sarah A. Moore12Stroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityStroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityNewcastle upon Tyne Hospitals NHS Foundation Trust, Clinical Ageing Research Unit, Campus for Ageing and VitalityDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Science, Northumbria UniversityInstitute of Translational and Clinical Research, Faculty of Medical Sciences, Newcastle UniversityStroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityNewcastle upon Tyne Hospitals NHS Foundation Trust, Clinical Ageing Research Unit, Campus for Ageing and VitalityService user. Contact via Stroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityAuckland University of TechnologyStroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityStroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityNewcastle upon Tyne Hospitals NHS Foundation Trust, Clinical Ageing Research Unit, Campus for Ageing and VitalityStroke Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle UniversityAbstract Background Gait impairment limiting mobility and restricting activities is common after stroke. Auditory rhythmical cueing (ARC) uses a metronome beat delivered during exercise to train stepping and early work reports gait improvements. This study aimed to establish the feasibility of a full scale multicentre randomised controlled trial to evaluate an ARC gait and balance training programme for use by stroke survivors in the home and outdoors. Methods A parallel-group observer-blind pilot randomised controlled trial was conducted. Adults within 2 years of stroke with a gait-related mobility impairment were recruited from four NHS stroke services and randomised to an ARC gait and balance training programme (intervention) or the training programme without ARC (control). Both programmes consisted of 3x30 min sessions per week for 6 weeks undertaken at home/nearby outdoor community. One session per week was supervised and the remainder self-managed. Gait and balance performance assessments were undertaken at baseline, 6 and 10 weeks. Key trial outcomes included recruitment and retention rates, programme adherence, assessment data completeness and safety. Results Between November 2018 and February 2020, 59 participants were randomised (intervention n=30, control n=29), mean recruitment rate 4/month. At baseline, 6 weeks and 10 weeks, research assessments were conducted for 59/59 (100%), 47/59 (80%) and 42/59 (71%) participants, respectively. Missing assessments were largely due to discontinuation of data collection from mid-March 2020 because of the UK COVID-19 pandemic lockdown. The proportion of participants with complete data for each individual performance assessment ranged from 100% at baseline to 68% at 10 weeks. In the intervention group, 433/540 (80%) total programme exercise sessions were undertaken, in the control group, 390/522 (75%). Falls were reported by five participants in the intervention group, six in the control group. Three serious adverse events occurred, all unrelated to the study. Conclusion We believe that a definitive multicentre RCT to evaluate the ARC gait and balance training programme is feasible. Recruitment, programme adherence and safety were all acceptable. Although we consider that the retention rate and assessment data completeness were not sufficient for a future trial, this was largely due to the UK COVID-19 pandemic lockdown. Trial registration ISRCTN, ISRCTN10874601 , Registered on 05/03/2018,https://doi.org/10.1186/s40814-022-01193-yStrokeGaitExerciseRehabilitationAuditory rhythmical cueingPilot randomized controlled trial |
| spellingShingle | Lisa Shaw Patricia McCue Philip Brown Christopher Buckley Silvia Del Din Richard Francis Heather Hunter Allen Lambert Sue Lord Christopher I. M. Price Helen Rodgers Lynn Rochester Sarah A. Moore Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial Pilot and Feasibility Studies Stroke Gait Exercise Rehabilitation Auditory rhythmical cueing Pilot randomized controlled trial |
| title | Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial |
| title_full | Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial |
| title_fullStr | Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial |
| title_full_unstemmed | Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial |
| title_short | Auditory rhythmical cueing to improve gait in community-dwelling stroke survivors (ACTIVATE): a pilot randomised controlled trial |
| title_sort | auditory rhythmical cueing to improve gait in community dwelling stroke survivors activate a pilot randomised controlled trial |
| topic | Stroke Gait Exercise Rehabilitation Auditory rhythmical cueing Pilot randomized controlled trial |
| url | https://doi.org/10.1186/s40814-022-01193-y |
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