Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea
Evidence suggests that the COVID-19 pandemic negatively impacts tuberculosis (TB) activities. As TB and COVID-19 have similar symptoms, we assessed the effectiveness of integrated TB/COVID-19 screening in Guinea and Niger. From May to December 2020, TB screening was offered to symptomatic patients a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/7/9/228 |
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| author | Aboubacar Sidiki Magassouba Souleymane Mahamadou Bassirou Almamy Amara Touré Boubacar Djelo Diallo Soumana Alphazazi Diao Cissé Mohamed Sitan Keita Elhadj Saidou Seyabatou Adama Marie Bangoura Hugues Asken Traoré Tom Decroo Jonathon R. Campbell Vanessa Veronese Corinne Simone Collette Merle |
| author_facet | Aboubacar Sidiki Magassouba Souleymane Mahamadou Bassirou Almamy Amara Touré Boubacar Djelo Diallo Soumana Alphazazi Diao Cissé Mohamed Sitan Keita Elhadj Saidou Seyabatou Adama Marie Bangoura Hugues Asken Traoré Tom Decroo Jonathon R. Campbell Vanessa Veronese Corinne Simone Collette Merle |
| author_sort | Aboubacar Sidiki Magassouba |
| collection | DOAJ |
| description | Evidence suggests that the COVID-19 pandemic negatively impacts tuberculosis (TB) activities. As TB and COVID-19 have similar symptoms, we assessed the effectiveness of integrated TB/COVID-19 screening in Guinea and Niger. From May to December 2020, TB screening was offered to symptomatic patients after a negative COVID-19 PCR test or after recovery from COVID-19 in Guinea. From December 2020 to March 2021, all presumptive COVID-19 patients with respiratory symptoms were tested simultaneously for COVID-19 and TB in Niger. We assessed the TB detection yield and used micro-costing to estimate the costs associated with both screening algorithms. A total of 863 individuals (758 in Guinea, and 105 in Niger), who were mostly male (60%) and with a median age of 34 (IQR: 26–45), were screened for TB. Reported symptoms were cough ≥2 weeks (49%), fever (45%), and weight loss (30%). Overall, 61 patients (7%) tested positive for COVID-19 (13 in Guinea, 48 in Niger) and 43 (4.9%) were diagnosed with TB disease (35 or 4.6% in Guinea, and 8 or 7.6% in Niger). The cost per person initiating TB treatment was USD $367 in Guinea and $566 in Niger. Overall, the yield of both approaches was high, and the cost was modest. Optimizing integrated COVID-19/TB screening may support maintaining TB detection during the ongoing pandemic. |
| first_indexed | 2024-03-09T22:19:22Z |
| format | Article |
| id | doaj.art-8f41f675e3e947d3ba22ad1ea3598fab |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-09T22:19:22Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-8f41f675e3e947d3ba22ad1ea3598fab2023-11-23T19:18:02ZengMDPI AGTropical Medicine and Infectious Disease2414-63662022-09-017922810.3390/tropicalmed7090228Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and GuineaAboubacar Sidiki Magassouba0Souleymane Mahamadou Bassirou1Almamy Amara Touré2Boubacar Djelo Diallo3Soumana Alphazazi4Diao Cissé5Mohamed Sitan Keita6Elhadj Saidou Seyabatou7Adama Marie Bangoura8Hugues Asken Traoré9Tom Decroo10Jonathon R. Campbell11Vanessa Veronese12Corinne Simone Collette Merle13Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry BP 1147, GuineaNational TB Programme, Niamey 12913, NigerDepartment of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry BP 1147, GuineaNational TB Programme, Conakry BP 1147, GuineaNational TB Programme, Niamey 12913, NigerNational Centre of Training and Recherche in Rural Health of Mafèrinyah, Forécariah BP 2649, GuineaDepartment of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry BP 1147, GuineaNational TB Programme, Niamey 12913, NigerNational TB Programme, Conakry BP 1147, GuineaThe Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, 1211 Geneva, SwitzerlandDepartment of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerpen, BelgiumDepartment of Epidemiology, Biostatistics and Occupational Health and The McGill International TB Centre, McGill University, 5252 Blvd de Maisonneuve West, Montreal, QC H4A 3S5, CanadaThe Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, 1211 Geneva, SwitzerlandThe Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, 1211 Geneva, SwitzerlandEvidence suggests that the COVID-19 pandemic negatively impacts tuberculosis (TB) activities. As TB and COVID-19 have similar symptoms, we assessed the effectiveness of integrated TB/COVID-19 screening in Guinea and Niger. From May to December 2020, TB screening was offered to symptomatic patients after a negative COVID-19 PCR test or after recovery from COVID-19 in Guinea. From December 2020 to March 2021, all presumptive COVID-19 patients with respiratory symptoms were tested simultaneously for COVID-19 and TB in Niger. We assessed the TB detection yield and used micro-costing to estimate the costs associated with both screening algorithms. A total of 863 individuals (758 in Guinea, and 105 in Niger), who were mostly male (60%) and with a median age of 34 (IQR: 26–45), were screened for TB. Reported symptoms were cough ≥2 weeks (49%), fever (45%), and weight loss (30%). Overall, 61 patients (7%) tested positive for COVID-19 (13 in Guinea, 48 in Niger) and 43 (4.9%) were diagnosed with TB disease (35 or 4.6% in Guinea, and 8 or 7.6% in Niger). The cost per person initiating TB treatment was USD $367 in Guinea and $566 in Niger. Overall, the yield of both approaches was high, and the cost was modest. Optimizing integrated COVID-19/TB screening may support maintaining TB detection during the ongoing pandemic.https://www.mdpi.com/2414-6366/7/9/228COVID-19tuberculosisactive TB screeningGuineaNiger |
| spellingShingle | Aboubacar Sidiki Magassouba Souleymane Mahamadou Bassirou Almamy Amara Touré Boubacar Djelo Diallo Soumana Alphazazi Diao Cissé Mohamed Sitan Keita Elhadj Saidou Seyabatou Adama Marie Bangoura Hugues Asken Traoré Tom Decroo Jonathon R. Campbell Vanessa Veronese Corinne Simone Collette Merle Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea Tropical Medicine and Infectious Disease COVID-19 tuberculosis active TB screening Guinea Niger |
| title | Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea |
| title_full | Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea |
| title_fullStr | Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea |
| title_full_unstemmed | Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea |
| title_short | Evaluating the Effectiveness of a Novel Systematic Screening Approach for Tuberculosis among Individuals Suspected or Recovered from COVID-19: Experiences from Niger and Guinea |
| title_sort | evaluating the effectiveness of a novel systematic screening approach for tuberculosis among individuals suspected or recovered from covid 19 experiences from niger and guinea |
| topic | COVID-19 tuberculosis active TB screening Guinea Niger |
| url | https://www.mdpi.com/2414-6366/7/9/228 |
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