Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex
Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin–Tb(III) in methanol, characterized by using elemental analysis, UV–visible and evaluation of its antioxidant properties. Methods: T...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2014-01-01
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| Series: | Advanced Pharmaceutical Bulletin |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-101.pdf |
| _version_ | 1811297080431345664 |
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| author | Jafar Ezzati Nazhad Dolatabadi Ahad Mokhtarzadeh Seyed Morteza Ghareghoran Gholamreza Dehghan |
| author_facet | Jafar Ezzati Nazhad Dolatabadi Ahad Mokhtarzadeh Seyed Morteza Ghareghoran Gholamreza Dehghan |
| author_sort | Jafar Ezzati Nazhad Dolatabadi |
| collection | DOAJ |
| description | Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin–Tb(III) in methanol, characterized by using elemental analysis, UV–visible and evaluation of its antioxidant properties.
Methods: The formation of complexes is realized from the UV–visible spectra which shows that the successive formation of Quercetin–Tb(III) occurs. To find out the antioxidant activity variation and the role of Tb(III) ion on the antioxidant activity of the complexes different radical scavenging methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and 2,2′-azinobis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) were used.
Results: The results from DPPH, ABTS and FRAP methods showed that Quercetin and Quercetin–Tb(III) complex are capable of donating electron or hydrogen atom, and consequently could react with free radicals or terminate chain reactions in a time- and dose-dependent manner.
Conclusion: This study showed that the chelation of metal ions by Quercetin decrease the redox potential of Quercetin-metal complex. |
| first_indexed | 2024-04-13T05:58:44Z |
| format | Article |
| id | doaj.art-8f44863ecfbf4e3a91ceafc895442518 |
| institution | Directory Open Access Journal |
| issn | 2228-5881 2251-7308 |
| language | English |
| last_indexed | 2024-04-13T05:58:44Z |
| publishDate | 2014-01-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj.art-8f44863ecfbf4e3a91ceafc8954425182022-12-22T02:59:32ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082014-01-014210110410.5681/apb.2014.016Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) ComplexJafar Ezzati Nazhad Dolatabadi0Ahad Mokhtarzadeh1Seyed Morteza Ghareghoran2Gholamreza Dehghan3Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Plant Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin–Tb(III) in methanol, characterized by using elemental analysis, UV–visible and evaluation of its antioxidant properties. Methods: The formation of complexes is realized from the UV–visible spectra which shows that the successive formation of Quercetin–Tb(III) occurs. To find out the antioxidant activity variation and the role of Tb(III) ion on the antioxidant activity of the complexes different radical scavenging methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and 2,2′-azinobis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) were used. Results: The results from DPPH, ABTS and FRAP methods showed that Quercetin and Quercetin–Tb(III) complex are capable of donating electron or hydrogen atom, and consequently could react with free radicals or terminate chain reactions in a time- and dose-dependent manner. Conclusion: This study showed that the chelation of metal ions by Quercetin decrease the redox potential of Quercetin-metal complex.http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-101.pdfFlavonoidAntioxidantQuercetin–Tb(III) complexDPPHFRAPABTS |
| spellingShingle | Jafar Ezzati Nazhad Dolatabadi Ahad Mokhtarzadeh Seyed Morteza Ghareghoran Gholamreza Dehghan Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex Advanced Pharmaceutical Bulletin Flavonoid Antioxidant Quercetin–Tb(III) complex DPPH FRAP ABTS |
| title | Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex |
| title_full | Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex |
| title_fullStr | Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex |
| title_full_unstemmed | Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex |
| title_short | Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex |
| title_sort | synthesis characterization and antioxidant property of quercetin tb iii complex |
| topic | Flavonoid Antioxidant Quercetin–Tb(III) complex DPPH FRAP ABTS |
| url | http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-101.pdf |
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