Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images

Due to the periodic contraction of the heart, a pulse-shaped course of the blood velocity is caused in the aortic system. The speed at which this pulse wave moves is called pulse wave velocity (PWV). Since it depends, among other parameters, on the elasticity of the vascular wall, it can be used cli...

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Main Authors: Schareck Constantin, Oechtering Thekla, Frydrychowicz Alex, Koch Martin
Format: Article
Language:English
Published: De Gruyter 2018-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2018-0114
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author Schareck Constantin
Oechtering Thekla
Frydrychowicz Alex
Koch Martin
author_facet Schareck Constantin
Oechtering Thekla
Frydrychowicz Alex
Koch Martin
author_sort Schareck Constantin
collection DOAJ
description Due to the periodic contraction of the heart, a pulse-shaped course of the blood velocity is caused in the aortic system. The speed at which this pulse wave moves is called pulse wave velocity (PWV). Since it depends, among other parameters, on the elasticity of the vascular wall, it can be used clinically as an indicator of atherosclerotic changes and, above all, as a measure of the risk of stroke for hypertensive patients. PWV can be determined non-invasively if the blood flow in the aorta is measured via flow-sensitive MRI. Within the scope of this work, existing phase-contrast (PC) image analysis algorithms, resulting in the PWV, were embedded in a graphical user interface (GUI). These algorithms were only able to evaluate PC images which were acquired on a Philips tomograph. Therefore they have been extended for the analysis of PC images acquired on a Siemens tomograph.
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spelling doaj.art-8f451509dd28488eaf16805af52075022023-08-21T06:42:02ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042018-09-014147748010.1515/cdbme-2018-0114cdbme-2018-0114Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance imagesSchareck Constantin0Oechtering Thekla1Frydrychowicz Alex2Koch Martin3Institute of Medical Engineering, Universität zu Lübeck,Lübeck, GermanyClinic of Radiology and Nuclear Medicine, Universitätsklinikum Schleswig-Holstein,Lübeck, GermanyClinic of Radiology and Nuclear Medicine, Universitätsklinikum Schleswig-Holstein,Lübeck, GermanyInstitute of Medical Engineering,Lübeck, GermanyDue to the periodic contraction of the heart, a pulse-shaped course of the blood velocity is caused in the aortic system. The speed at which this pulse wave moves is called pulse wave velocity (PWV). Since it depends, among other parameters, on the elasticity of the vascular wall, it can be used clinically as an indicator of atherosclerotic changes and, above all, as a measure of the risk of stroke for hypertensive patients. PWV can be determined non-invasively if the blood flow in the aorta is measured via flow-sensitive MRI. Within the scope of this work, existing phase-contrast (PC) image analysis algorithms, resulting in the PWV, were embedded in a graphical user interface (GUI). These algorithms were only able to evaluate PC images which were acquired on a Philips tomograph. Therefore they have been extended for the analysis of PC images acquired on a Siemens tomograph.https://doi.org/10.1515/cdbme-2018-0114pulse wave velocityphase contrast mri
spellingShingle Schareck Constantin
Oechtering Thekla
Frydrychowicz Alex
Koch Martin
Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
Current Directions in Biomedical Engineering
pulse wave velocity
phase contrast mri
title Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
title_full Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
title_fullStr Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
title_full_unstemmed Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
title_short Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images
title_sort development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase contrast magnetic resonance images
topic pulse wave velocity
phase contrast mri
url https://doi.org/10.1515/cdbme-2018-0114
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