Nicotine exacerbates tacrolimus-induced renal injury by programmed cell death

Nicotine exacerbates tacrolimus-induced renal injury by programmed cell death

Background/Aims Cigarette smoking is an important modifiable risk factor in kidney disease progression. However, the underlying mechanisms for this are lacking. This study aimed to assess whether nicotine (NIC), a major toxic component of cigarette smoking, would exacerbates tacrolimus (TAC)-induced...

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Bibliographic Details
Main Authors: Yu Ji Jiang, Sheng Cui, Kang Luo, Jun Ding, Qi Yan Nan, Shang Guo Piao, Mei Ying Xuan, Hai Lan Zheng, Yong Jie Jin, Ji Zhe Jin, Jung Pyo Lee, Byung Ha Chung, Bum Soon Choi, Chul Woo Yang, Can Li
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2021-11-01
Series:The Korean Journal of Internal Medicine
Subjects:
nicotine
tacrolimus
apoptosis
autophagy
mitochondria
Online Access:http://www.kjim.org/upload/pdf/kjim-2021-326.pdf

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