Prostate Cancer and Its Mimics—A Pictorial Review
Background: Multiparametric prostate MRI (mpMRI) is gaining wider recommendations for diagnosing and following up on prostate cancer. However, despite the high accuracy of mpMRI, false positive and false negative results are reported. Some of these may be related to normal anatomic structures, benig...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/14/3682 |
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| author | Anna Żurowska Rafał Pęksa Michał Bieńkowski Katarzyna Skrobisz Marek Sowa Marcin Matuszewski Wojciech Biernat Edyta Szurowska |
| author_facet | Anna Żurowska Rafał Pęksa Michał Bieńkowski Katarzyna Skrobisz Marek Sowa Marcin Matuszewski Wojciech Biernat Edyta Szurowska |
| author_sort | Anna Żurowska |
| collection | DOAJ |
| description | Background: Multiparametric prostate MRI (mpMRI) is gaining wider recommendations for diagnosing and following up on prostate cancer. However, despite the high accuracy of mpMRI, false positive and false negative results are reported. Some of these may be related to normal anatomic structures, benign lesions that may mimic cancer, or poor-quality images that hamper interpretation. The aim of this review is to discuss common potential pitfalls in the interpretation of mpMRI. Methods: mpMRI of the prostates was performed on 3T MRI scanners (Philips Achieva or Siemens Magnetom Vida) according to European Society of Urogenital Radiology (ESUR) guidelines and technical requirements. Results: This pictorial review discusses normal anatomical structures such as the anterior fibromuscular stroma, periprostatic venous plexus, central zone, and benign conditions such as benign prostate hyperplasia (BPH), post-biopsy hemorrhage, prostatitis, and abscess that may imitate prostate cancer, as well as the appearance of prostate cancer occurring in these locations. Furthermore, suggestions on how to avoid these pitfalls are provided, and the impact of image quality is also discussed. Conclusions: In an era of accelerating prostate mpMRI and high demand for high-quality interpretation of the scans, radiologists should be aware of these potential pitfalls to improve their diagnostic accuracy. |
| first_indexed | 2024-03-11T01:12:47Z |
| format | Article |
| id | doaj.art-8f53d49451104f42b156edeca818c030 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T01:12:47Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-8f53d49451104f42b156edeca818c0302023-11-18T18:42:38ZengMDPI AGCancers2072-66942023-07-011514368210.3390/cancers15143682Prostate Cancer and Its Mimics—A Pictorial ReviewAnna Żurowska0Rafał Pęksa1Michał Bieńkowski2Katarzyna Skrobisz3Marek Sowa4Marcin Matuszewski5Wojciech Biernat6Edyta Szurowska7Second Department of Radiology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Pathomorphology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Pathomorphology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Radiology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Urology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Urology, Medical University of Gdańsk, 80-214 Gdańsk, PolandDepartment of Pathomorphology, Medical University of Gdańsk, 80-214 Gdańsk, PolandSecond Department of Radiology, Medical University of Gdańsk, 80-214 Gdańsk, PolandBackground: Multiparametric prostate MRI (mpMRI) is gaining wider recommendations for diagnosing and following up on prostate cancer. However, despite the high accuracy of mpMRI, false positive and false negative results are reported. Some of these may be related to normal anatomic structures, benign lesions that may mimic cancer, or poor-quality images that hamper interpretation. The aim of this review is to discuss common potential pitfalls in the interpretation of mpMRI. Methods: mpMRI of the prostates was performed on 3T MRI scanners (Philips Achieva or Siemens Magnetom Vida) according to European Society of Urogenital Radiology (ESUR) guidelines and technical requirements. Results: This pictorial review discusses normal anatomical structures such as the anterior fibromuscular stroma, periprostatic venous plexus, central zone, and benign conditions such as benign prostate hyperplasia (BPH), post-biopsy hemorrhage, prostatitis, and abscess that may imitate prostate cancer, as well as the appearance of prostate cancer occurring in these locations. Furthermore, suggestions on how to avoid these pitfalls are provided, and the impact of image quality is also discussed. Conclusions: In an era of accelerating prostate mpMRI and high demand for high-quality interpretation of the scans, radiologists should be aware of these potential pitfalls to improve their diagnostic accuracy.https://www.mdpi.com/2072-6694/15/14/3682prostate cancermagnetic resonance imaging (MRI)mpMRIpitfallsdifferential diagnosis |
| spellingShingle | Anna Żurowska Rafał Pęksa Michał Bieńkowski Katarzyna Skrobisz Marek Sowa Marcin Matuszewski Wojciech Biernat Edyta Szurowska Prostate Cancer and Its Mimics—A Pictorial Review Cancers prostate cancer magnetic resonance imaging (MRI) mpMRI pitfalls differential diagnosis |
| title | Prostate Cancer and Its Mimics—A Pictorial Review |
| title_full | Prostate Cancer and Its Mimics—A Pictorial Review |
| title_fullStr | Prostate Cancer and Its Mimics—A Pictorial Review |
| title_full_unstemmed | Prostate Cancer and Its Mimics—A Pictorial Review |
| title_short | Prostate Cancer and Its Mimics—A Pictorial Review |
| title_sort | prostate cancer and its mimics a pictorial review |
| topic | prostate cancer magnetic resonance imaging (MRI) mpMRI pitfalls differential diagnosis |
| url | https://www.mdpi.com/2072-6694/15/14/3682 |
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