Prematurity—Risk Factor or Coincidence in Congenital Glaucoma?
<i>Background and</i> <i>Objective:</i> To correlate the intraocular pressure with the postconceptional age and identify a statistically significant connection between congenital glaucoma and prematurity. <i>Materials and</i> <i>Methods:</i> The curren...
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| Format: | Article |
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MDPI AG
2022-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/3/334 |
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| author | Christiana D. M. Dragosloveanu Vasile Potop Valeria Coviltir Valentin Dinu Mihai Păsărică Irina L. Ducan Călina Maier Şerban Dragosloveanu |
| author_facet | Christiana D. M. Dragosloveanu Vasile Potop Valeria Coviltir Valentin Dinu Mihai Păsărică Irina L. Ducan Călina Maier Şerban Dragosloveanu |
| author_sort | Christiana D. M. Dragosloveanu |
| collection | DOAJ |
| description | <i>Background and</i> <i>Objective:</i> To correlate the intraocular pressure with the postconceptional age and identify a statistically significant connection between congenital glaucoma and prematurity. <i>Materials and</i> <i>Methods:</i> The current paper is a retrospective, comparative, case-control study. Data collection featured maternal age, gestational age at birth, birth weight, and intraocular ocular pressure (IOP) measurements. <i>Results:</i> Forty-two eyes of 21 children underwent examination. The participants were assigned into two groups. The Preterm-Glaucoma (PG) group included eight preterm-born children diagnosed with glaucoma, whereas the Preterm (P) group was comprised of premature newborns without the aforementioned condition. There was no statistically relevant difference in birth weight (<i>p</i> = 0.691078) nor in mean gestational age (<i>p</i> = 0.752623) between the two groups. The mean IOP in the PG group was 23.813 ± 4.5493, whereas in the P group, it ranged around 13.231 ± 1.0699, <i>p</i> < 0.0001. Using mixed-effects models, we obtained a reduction in IOP of 0.45 mmHg per week in the first month of life. A further weekly reduction of 0.36 mmHg was achieved in the next two months. <i>Conclusions:</i> The mean IOP of prematurely born children decreased with age. Our findings correlate with previously conducted studies, however, the drop in IOP values exceeded any data published so far. We found no correlation between prematurity and the incidence of congenital glaucoma. |
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| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T13:24:28Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-8f5798d387df42b18b328d613c2a10192023-11-30T21:25:27ZengMDPI AGMedicina1010-660X1648-91442022-02-0158333410.3390/medicina58030334Prematurity—Risk Factor or Coincidence in Congenital Glaucoma?Christiana D. M. Dragosloveanu0Vasile Potop1Valeria Coviltir2Valentin Dinu3Mihai Păsărică4Irina L. Ducan5Călina Maier6Şerban Dragosloveanu7Department of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Ophthalmology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Orthopedics, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania<i>Background and</i> <i>Objective:</i> To correlate the intraocular pressure with the postconceptional age and identify a statistically significant connection between congenital glaucoma and prematurity. <i>Materials and</i> <i>Methods:</i> The current paper is a retrospective, comparative, case-control study. Data collection featured maternal age, gestational age at birth, birth weight, and intraocular ocular pressure (IOP) measurements. <i>Results:</i> Forty-two eyes of 21 children underwent examination. The participants were assigned into two groups. The Preterm-Glaucoma (PG) group included eight preterm-born children diagnosed with glaucoma, whereas the Preterm (P) group was comprised of premature newborns without the aforementioned condition. There was no statistically relevant difference in birth weight (<i>p</i> = 0.691078) nor in mean gestational age (<i>p</i> = 0.752623) between the two groups. The mean IOP in the PG group was 23.813 ± 4.5493, whereas in the P group, it ranged around 13.231 ± 1.0699, <i>p</i> < 0.0001. Using mixed-effects models, we obtained a reduction in IOP of 0.45 mmHg per week in the first month of life. A further weekly reduction of 0.36 mmHg was achieved in the next two months. <i>Conclusions:</i> The mean IOP of prematurely born children decreased with age. Our findings correlate with previously conducted studies, however, the drop in IOP values exceeded any data published so far. We found no correlation between prematurity and the incidence of congenital glaucoma.https://www.mdpi.com/1648-9144/58/3/334congenital glaucomarisk factorsprematurity |
| spellingShingle | Christiana D. M. Dragosloveanu Vasile Potop Valeria Coviltir Valentin Dinu Mihai Păsărică Irina L. Ducan Călina Maier Şerban Dragosloveanu Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? Medicina congenital glaucoma risk factors prematurity |
| title | Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? |
| title_full | Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? |
| title_fullStr | Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? |
| title_full_unstemmed | Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? |
| title_short | Prematurity—Risk Factor or Coincidence in Congenital Glaucoma? |
| title_sort | prematurity risk factor or coincidence in congenital glaucoma |
| topic | congenital glaucoma risk factors prematurity |
| url | https://www.mdpi.com/1648-9144/58/3/334 |
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