Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis
We report 4 cases of hypopharyngeal cancer preoperatively suspected with synchronous lymph node metastases. Pathologic lymph node metastasis was confirmed in three of the four cases. All 4 cases underwent endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2023-01-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | https://www.karger.com/Article/FullText/528424 |
| _version_ | 1828045163006525440 |
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| author | Shinya Sugimoto Tomohito Fuke Daisuke Kobayashi Mamika Kaneko Taishi Temma Tatsuma Nomura Nobuyuki Tsuda Mayu Kawabata Ryutaro Matsushima Hirohisa Hisada Satoshi Hayashi Toji Murabayashi Jun Oyamada Akira Kamei Nobukazu Fuwa Tadashi Yabana Hiroyuki Yamada Hayato Nakagawa |
| author_facet | Shinya Sugimoto Tomohito Fuke Daisuke Kobayashi Mamika Kaneko Taishi Temma Tatsuma Nomura Nobuyuki Tsuda Mayu Kawabata Ryutaro Matsushima Hirohisa Hisada Satoshi Hayashi Toji Murabayashi Jun Oyamada Akira Kamei Nobukazu Fuwa Tadashi Yabana Hiroyuki Yamada Hayato Nakagawa |
| author_sort | Shinya Sugimoto |
| collection | DOAJ |
| description | We report 4 cases of hypopharyngeal cancer preoperatively suspected with synchronous lymph node metastases. Pathologic lymph node metastasis was confirmed in three of the four cases. All 4 cases underwent endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD) and subsequent lymph node dissection as an optional treatment rather than the standard treatment. Peroral resection for primary site was selected because of the expected decline in quality of life (QoL) after radical surgery. Among 4 patients, one developed local recurrence; however, the other three remained recurrence-free and survived without any additional treatment. Furthermore, the patient who developed local recurrence had a recurrence-free survival for more than 5 years, with additional chemoradiation therapy. No disorders in speech, swallowing, or breathing was observed during the follow-up period. ELPS combined with ESD is generally indicated for laryngopharyngeal cancer without synchronous lymph node metastasis. However, this can be a treatment option for patients may wish to preserve a greater QoL after treatment. In the future, when more data on the results and long-term prognosis of this treatment are accumulated, it may be possible to discuss its validity further. |
| first_indexed | 2024-04-10T18:07:18Z |
| format | Article |
| id | doaj.art-8f5f3b4885c54c969d48d9af81b9fdc1 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-04-10T18:07:18Z |
| publishDate | 2023-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-8f5f3b4885c54c969d48d9af81b9fdc12023-02-02T12:54:54ZengKarger PublishersCase Reports in Gastroenterology1662-06312023-01-0117111310.1159/000528424528424Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node MetastasisShinya Sugimoto0Tomohito Fuke1https://orcid.org/0000-0002-9100-2903Daisuke Kobayashi2Mamika Kaneko3Taishi Temma4Tatsuma Nomura5Nobuyuki Tsuda6Mayu Kawabata7https://orcid.org/0000-0002-7314-5759Ryutaro Matsushima8Hirohisa Hisada9Satoshi Hayashi10Toji Murabayashi11Jun Oyamada12Akira Kamei13Nobukazu Fuwa14Tadashi Yabana15Hiroyuki Yamada16Hayato Nakagawa17Department of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Otolaryngology-Head and Neck Surgery, Ise Red Cross Hospital, Ise, JapanDepartment of Otolaryngology-Head and Neck Surgery, Ise Red Cross Hospital, Ise, JapanDepartment of Otolaryngology-Head and Neck Surgery, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology, Ise Red Cross Hospital, Ise, JapanDepartment of Radiation Oncology, Ise Red Cross Hospital, Ise, JapanDepartment of Pathology, Ise Red Cross Hospital, Ise, JapanDepartment of Otolaryngology-Head and Neck Surgery, Ise Red Cross Hospital, Ise, JapanDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, JapanWe report 4 cases of hypopharyngeal cancer preoperatively suspected with synchronous lymph node metastases. Pathologic lymph node metastasis was confirmed in three of the four cases. All 4 cases underwent endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD) and subsequent lymph node dissection as an optional treatment rather than the standard treatment. Peroral resection for primary site was selected because of the expected decline in quality of life (QoL) after radical surgery. Among 4 patients, one developed local recurrence; however, the other three remained recurrence-free and survived without any additional treatment. Furthermore, the patient who developed local recurrence had a recurrence-free survival for more than 5 years, with additional chemoradiation therapy. No disorders in speech, swallowing, or breathing was observed during the follow-up period. ELPS combined with ESD is generally indicated for laryngopharyngeal cancer without synchronous lymph node metastasis. However, this can be a treatment option for patients may wish to preserve a greater QoL after treatment. In the future, when more data on the results and long-term prognosis of this treatment are accumulated, it may be possible to discuss its validity further.https://www.karger.com/Article/FullText/528424laryngopharyngeal cancerendoscopic laryngopharyngeal surgeryendoscopic submucosal dissectionsynchronous lymph node metastasislymph node dissection |
| spellingShingle | Shinya Sugimoto Tomohito Fuke Daisuke Kobayashi Mamika Kaneko Taishi Temma Tatsuma Nomura Nobuyuki Tsuda Mayu Kawabata Ryutaro Matsushima Hirohisa Hisada Satoshi Hayashi Toji Murabayashi Jun Oyamada Akira Kamei Nobukazu Fuwa Tadashi Yabana Hiroyuki Yamada Hayato Nakagawa Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis Case Reports in Gastroenterology laryngopharyngeal cancer endoscopic laryngopharyngeal surgery endoscopic submucosal dissection synchronous lymph node metastasis lymph node dissection |
| title | Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis |
| title_full | Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis |
| title_fullStr | Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis |
| title_full_unstemmed | Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis |
| title_short | Endoscopic Laryngopharyngeal Surgery Combined with Endoscopic Submucosal Dissection as a Treatment Option for Superficial Hypopharyngeal Cancer with Suspected Synchronous Lymph Node Metastasis |
| title_sort | endoscopic laryngopharyngeal surgery combined with endoscopic submucosal dissection as a treatment option for superficial hypopharyngeal cancer with suspected synchronous lymph node metastasis |
| topic | laryngopharyngeal cancer endoscopic laryngopharyngeal surgery endoscopic submucosal dissection synchronous lymph node metastasis lymph node dissection |
| url | https://www.karger.com/Article/FullText/528424 |
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