Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study
Introduction-Nosocomial infections (NI) are a real public health problem, especially in intensive care units, where the risk of NI and death is higher, mainly when multidrug-resistant bacteria cause these infections. Objective- to determine the main risk factors for NI as well as the prognostic...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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University of Oran 1
2020-12-01
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| Series: | Journal de la Faculté de Médecine d'Oran |
| Subjects: | |
| Online Access: | https://www.ajol.info/index.php/jfmo/article/view/226764 |
| _version_ | 1797741138373771264 |
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| author | Abdessamad Dali Ali Houaria Beldjilali Fouzia Aggag Mohamed Zina Salah Ouhadj Radia Dali Yahia Khadidja Meddeber Nori Midoun |
| author_facet | Abdessamad Dali Ali Houaria Beldjilali Fouzia Aggag Mohamed Zina Salah Ouhadj Radia Dali Yahia Khadidja Meddeber Nori Midoun |
| author_sort | Abdessamad Dali Ali |
| collection | DOAJ |
| description |
Introduction-Nosocomial infections (NI) are a real public health problem, especially in intensive care units, where the risk of NI and death is higher, mainly when multidrug-resistant bacteria cause these infections.
Objective- to determine the main risk factors for NI as well as the prognostic factors associated with the occurrence of death in adult intensive care units.
Methods-This is an unmatched case-control study, nested in the cohort of patients admitted to the intensive care unit of the medico-surgical emergencies of the Oran hospital and university hospital (Algeria), from June 3, 2012 to December 31, 2013. The cases (n=73) corresponded to patients who developed a NI and the controls (n=232) corresponded to those who were free from NI. The risk factors studied corresponded to exposures to the various invasive medical devices. To study the relationship between the different types of variables, the Chi-square test was used for the categorical variables and the Student test for the quantitative variables. The statistical significance level p has been set at 5%.
Results-In multifactorial analysis, male sex (aOR = 3,16, p = 0,03) and central venous catheterization duration greater than 8 days (aOR = 4,7, p = 0,01) were significantly associated with the occurrence of NI. The occurrence of death was associated with three prognostic factors, that is: age greater than 65 years (aOR = 4,31, p < 0,01), exposure to intubation (aOR = 9,49, p < 0,001) and the presence of central venous catheterization(aOR: 2,43, p = 0,02). The presence of NI regardless of its location was not associated with the occurrence of death.
Conclusion-Prolonged exposure to different invasive devices was the main risk factor for the development of NI in the intensive care unit. However, no significant associationwas found between the NI and the occurrence of death.
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| first_indexed | 2024-03-12T14:22:33Z |
| format | Article |
| id | doaj.art-8f6213dd3eb745ea9371935c45e95f02 |
| institution | Directory Open Access Journal |
| issn | 2571-9874 2602-6511 |
| language | English |
| last_indexed | 2024-03-12T14:22:33Z |
| publishDate | 2020-12-01 |
| publisher | University of Oran 1 |
| record_format | Article |
| series | Journal de la Faculté de Médecine d'Oran |
| spelling | doaj.art-8f6213dd3eb745ea9371935c45e95f022023-08-18T19:41:55ZengUniversity of Oran 1Journal de la Faculté de Médecine d'Oran2571-98742602-65112020-12-0142Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control studyAbdessamad Dali Ali0Houaria Beldjilali 1 Fouzia Aggag2Mohamed Zina 3Salah Ouhadj4Radia Dali Yahia 5Khadidja Meddeber6Nori Midoun7Service d’épidémiologie ,établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1Service d’épidémiologie ,établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1Service d’épidémiologie ,établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1Etablissement public de santé de proximité de Boutlelis,OranService d’épidémiologie ,établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1Service de microbiologie, établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1EHS CanastelService d’épidémiologie ,établissement hospitalo universitaire 1er novembre d’Oran ,Faculté de médecine, université Oran1 Introduction-Nosocomial infections (NI) are a real public health problem, especially in intensive care units, where the risk of NI and death is higher, mainly when multidrug-resistant bacteria cause these infections. Objective- to determine the main risk factors for NI as well as the prognostic factors associated with the occurrence of death in adult intensive care units. Methods-This is an unmatched case-control study, nested in the cohort of patients admitted to the intensive care unit of the medico-surgical emergencies of the Oran hospital and university hospital (Algeria), from June 3, 2012 to December 31, 2013. The cases (n=73) corresponded to patients who developed a NI and the controls (n=232) corresponded to those who were free from NI. The risk factors studied corresponded to exposures to the various invasive medical devices. To study the relationship between the different types of variables, the Chi-square test was used for the categorical variables and the Student test for the quantitative variables. The statistical significance level p has been set at 5%. Results-In multifactorial analysis, male sex (aOR = 3,16, p = 0,03) and central venous catheterization duration greater than 8 days (aOR = 4,7, p = 0,01) were significantly associated with the occurrence of NI. The occurrence of death was associated with three prognostic factors, that is: age greater than 65 years (aOR = 4,31, p < 0,01), exposure to intubation (aOR = 9,49, p < 0,001) and the presence of central venous catheterization(aOR: 2,43, p = 0,02). The presence of NI regardless of its location was not associated with the occurrence of death. Conclusion-Prolonged exposure to different invasive devices was the main risk factor for the development of NI in the intensive care unit. However, no significant associationwas found between the NI and the occurrence of death. https://www.ajol.info/index.php/jfmo/article/view/226764Attributable mortalityhealth care associated infectionsprognostic factors |
| spellingShingle | Abdessamad Dali Ali Houaria Beldjilali Fouzia Aggag Mohamed Zina Salah Ouhadj Radia Dali Yahia Khadidja Meddeber Nori Midoun Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study Journal de la Faculté de Médecine d'Oran Attributable mortality health care associated infections prognostic factors |
| title | Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study |
| title_full | Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study |
| title_fullStr | Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study |
| title_full_unstemmed | Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study |
| title_short | Risk factors and mortality associated with nosocomial infections in intensive care unit: a case-control study |
| title_sort | risk factors and mortality associated with nosocomial infections in intensive care unit a case control study |
| topic | Attributable mortality health care associated infections prognostic factors |
| url | https://www.ajol.info/index.php/jfmo/article/view/226764 |
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