ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells
ZNF185 is identified as a novel PKA substrate and found to be important for the organization of endothelial cell–cell junctions and suppression of vascular hyperpermeability by regulating the cAMP/PKA/RhoA signaling pathway.
Bibliographic Details
Main Authors: |
Soichiro Suzuki,
Fumiaki Ando,
Sae Kitagawa,
Yu Hara,
Tamami Fujiki,
Shintaro Mandai,
Koichiro Susa,
Takayasu Mori,
Eisei Sohara,
Tatemitsu Rai,
Shinichi Uchida |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2023-01-01
|
Series: | Communications Biology
|
Online Access: | https://doi.org/10.1038/s42003-023-04416-x
|