Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits
<p><strong>Introduction:</strong> Our aim was to evaluate effects of hemicastration in immature rabbits on the histology of the contralateral testis after puberty.</p><p><strong>Materials and Methods:</strong&...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences
2009-08-01
|
| Series: | Urology Journal |
| Online Access: | http://www.urologyjournal.org/index.php/uj/article/view/397 |
| _version_ | 1818753406742822912 |
|---|---|
| author | Kamyar Tavakkoli Tabassi Sakineh Amoueian Elena Saremi |
| author_facet | Kamyar Tavakkoli Tabassi Sakineh Amoueian Elena Saremi |
| author_sort | Kamyar Tavakkoli Tabassi |
| collection | DOAJ |
| description | <p><strong>Introduction:</strong> Our aim was to evaluate effects of hemicastration in immature rabbits on the histology of the contralateral testis after puberty.</p><p><strong>Materials and Methods:</strong> Eighteen immature male rabbits were randomly divided into two groups. The first group underwent right or left hemicastration and the second, sham operation. After their puberty, the rabbits underwent the second operation. In the former group the contralateral testis and in the latter, the right or left testis was removed and sent for pathologic examination. The two groups were compared in terms of Leydig cell count, testis volume, and seminiferous tubule count and diameter.</p><p><strong>Results:</strong> The mature rabbits’ mean weight at the orchiectomy time, seminiferous tubule count, and seminiferous tubules diameter did not show significant differences between two groups. However, testis volumes and Leydig cell count were significantly higher in the first group with hemicastration prior to puberty. The mean testis volume was 3.24 ± 2.06 mL in the first group and 1.4689 ± 0.85701 mL in the second group (P = .03), and the mean Leydig cell count in every 5 microscopic high-power fields was 86.22 ± 54.96 and 42.00 ± 18.09, respectively (P = .04).</p><p><strong>Conclusion:</strong> Our research demonstrated that prepubertal hemicastration in rabbits led to the compensatory hypertrophy in the contralateral testis after puberty and an increase in the number of the Leydig cells.</p> |
| first_indexed | 2024-12-18T05:06:51Z |
| format | Article |
| id | doaj.art-8f68757406194a49b07af95c8fcf7e43 |
| institution | Directory Open Access Journal |
| issn | 1735-1308 1735-546X |
| language | English |
| last_indexed | 2024-12-18T05:06:51Z |
| publishDate | 2009-08-01 |
| publisher | Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Urology Journal |
| spelling | doaj.art-8f68757406194a49b07af95c8fcf7e432022-12-21T21:20:00ZengUrology and Nephrology Research Center, Shahid Beheshti University of Medical SciencesUrology Journal1735-13081735-546X2009-08-0163199203Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature RabbitsKamyar Tavakkoli TabassiSakineh AmoueianElena Saremi<p><strong>Introduction:</strong> Our aim was to evaluate effects of hemicastration in immature rabbits on the histology of the contralateral testis after puberty.</p><p><strong>Materials and Methods:</strong> Eighteen immature male rabbits were randomly divided into two groups. The first group underwent right or left hemicastration and the second, sham operation. After their puberty, the rabbits underwent the second operation. In the former group the contralateral testis and in the latter, the right or left testis was removed and sent for pathologic examination. The two groups were compared in terms of Leydig cell count, testis volume, and seminiferous tubule count and diameter.</p><p><strong>Results:</strong> The mature rabbits’ mean weight at the orchiectomy time, seminiferous tubule count, and seminiferous tubules diameter did not show significant differences between two groups. However, testis volumes and Leydig cell count were significantly higher in the first group with hemicastration prior to puberty. The mean testis volume was 3.24 ± 2.06 mL in the first group and 1.4689 ± 0.85701 mL in the second group (P = .03), and the mean Leydig cell count in every 5 microscopic high-power fields was 86.22 ± 54.96 and 42.00 ± 18.09, respectively (P = .04).</p><p><strong>Conclusion:</strong> Our research demonstrated that prepubertal hemicastration in rabbits led to the compensatory hypertrophy in the contralateral testis after puberty and an increase in the number of the Leydig cells.</p>http://www.urologyjournal.org/index.php/uj/article/view/397 |
| spellingShingle | Kamyar Tavakkoli Tabassi Sakineh Amoueian Elena Saremi Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits Urology Journal |
| title | Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits |
| title_full | Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits |
| title_fullStr | Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits |
| title_full_unstemmed | Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits |
| title_short | Pattern of Compensatory Hypertrophy in Contralateral Testis After Unilateral Orchiectomy in Immature Rabbits |
| title_sort | pattern of compensatory hypertrophy in contralateral testis after unilateral orchiectomy in immature rabbits |
| url | http://www.urologyjournal.org/index.php/uj/article/view/397 |
| work_keys_str_mv | AT kamyartavakkolitabassi patternofcompensatoryhypertrophyincontralateraltestisafterunilateralorchiectomyinimmaturerabbits AT sakinehamoueian patternofcompensatoryhypertrophyincontralateraltestisafterunilateralorchiectomyinimmaturerabbits AT elenasaremi patternofcompensatoryhypertrophyincontralateraltestisafterunilateralorchiectomyinimmaturerabbits |