Determinants of Amyloid Formation for the Yeast Termination Factor Nab3.

Low complexity protein sequences are often intrinsically unstructured and many have the potential to polymerize into amyloid aggregates including filaments and hydrogels. RNA-binding proteins are unusually enriched in such sequences raising the question as to what function these domains serve in RNA...

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Bibliographic Details
Main Authors: Thomas W O'Rourke, Daniel Reines
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4783047?pdf=render