Retinal protective effects of topically administered agmatine on ischemic ocular injury caused by transient occlusion of the ophthalmic artery

Retinal protective effects of topically administered agmatine on ischemic ocular injury caused by transient occlusion of the ophthalmic artery

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Agmatine, an endogenous polyamine and putative neuromodulator, is known to have neuroprotective effects on various neurons in the central nervous system. We determined whether or not topically administered agmatine could reduce ischemic retinal injury. Transient ocular ischemia was achieved by intra...

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Bibliographic Details
Main Authors: S. Hong, H. Hara, M. Shimazawa, K. Hyakkoku, C.Y. Kim, G.J. Seong
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Agmatine
Apoptosis
Ischemia
Neuroprotection
Retina
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300005

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