O-GlcNAcylation: a new cancer hallmark?

O-GlcNAcylation: a new cancer hallmark?

O-linked N-acetylglucosaminylation (O-GlcNAcylation) is a reversible post-translational modification consisting in the addition of a sugar moiety to serine/threonine residues of cytosolic or nuclear proteins. Catalyzed by OGT and removed by OGA, this dynamic modification is dependent on environmenta...

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Bibliographic Details
Main Authors:	Yann eFardini, Vanessa eDehennaut, Tony eLefebvre, Tarik eISSAD
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-08-01
Series:	Frontiers in Endocrinology
Subjects:	Cell Cycle Transcription Factors Cancer epigenetics metastasis oncogenesis
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00099/full

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