Citrate as Cost-Efficient NADPH Regenerating Agent

Citrate as Cost-Efficient NADPH Regenerating Agent

The economically efficient utilization of NAD(P)H-dependent enzymes requires the regeneration of consumed reduction equivalents. Classically, this is done by substrate supplementation, and if necessary by addition of one or more enzymes. The simplest method thereof is whole cell NADPH regeneration....

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Bibliographic Details
Main Authors: Reinhard Oeggl, Timo Neumann, Jochem Gätgens, Diego Romano, Stephan Noack, Dörte Rother
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
citrate oxidation
oxidoreductase screening
nicotinamide cofactor
reduction equivalent regeneration
NADPH regeneration
cofactor regeneration
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00196/full

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