Yohimbine-Induced Reactivity of Heart Rate Variability in Unmedicated Depressed Patients With and Without Adverse Childhood Experience

Yohimbine-Induced Reactivity of Heart Rate Variability in Unmedicated Depressed Patients With and Without Adverse Childhood Experience

Stressful life events play a role in the pathogenesis of major depressive disorder (MDD) and many patients with MDD were exposed to developmental stress due to adverse childhood experiences (ACE). Furthermore, dysregulation of the autonomic nervous system and higher incidence of cardiovascular disea...

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Bibliographic Details
Main Authors: Christian Eric Deuter, Christian Otte, Katja Wingenfeld, Linn Kristina Kuehl
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Psychiatry
Subjects:
childhood trauma
early life maltreatment
adverse childhood experience
heart rate variability
major depressive disorder
yohimbine
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.734904/full

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