Brain Re-Irradiation Or Chemotherapy: a phase II randomised trial of re-irradiation and chemotherapy in patients with recurrent glioblastoma (BRIOChe) – protocol for a multi-centre open-label randomised trial

Brain Re-Irradiation Or Chemotherapy: a phase II randomised trial of re-irradiation and chemotherapy in patients with recurrent glioblastoma (BRIOChe) – protocol for a multi-centre open-label randomised trial

Introduction Glioblastoma (GBM) is the most common adult primary malignant brain tumour. The condition is incurable and, despite aggressive treatment at first presentation, almost all tumours recur after a median of 7 months. The aim of treatment at recurrence is to prolong survival and maintain hea...

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Main Authors: Stuart Currie, Alexandra Smith, David Sebag-Montefiore, Helen Bulbeck, Jane Hughes, Susan Short, Eleanor M Hudson, Samantha Noutch, Catherine Parbutt, Louise Murray, Joanne Webster, Sarah R Brown, Florien W Boele, Omar Al-Salihi, Helen Baines, Sharon Fernandez, John Lilley, Finbar Slevin
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/3/e078926.full

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