Cysteine and glycine-rich protein 3 (Crp3) as a critical regulator of elastolysis, inflammation, and smooth muscle cell apoptosis in abdominal aortic aneurysm development

Cysteine and glycine-rich protein 3 (Crp3) as a critical regulator of elastolysis, inflammation, and smooth muscle cell apoptosis in abdominal aortic aneurysm development

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease for which surgical or endovascular repair are the only currently available therapeutic strategies. The development of AAA involves the breakdown of elastic fibers (elastolysis), infiltration of inflammatory cells, and apoptosis o...

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Bibliographic Details
Main Authors: Ana Barbosa Marcondes de Mattos, Joao Carlos Ribeiro-Silva, Miriam Helena Fonseca-Alaniz, Iuri Cordeiro Valadão, Erasmo Simão da Silva, Jose Eduardo Krieger, Ayumi Aurea Miyakawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Physiology
Subjects:
abdominal aortic aneurysm
cysteine and glycine-rich protein-3
smooth muscle cell
apoptosis
elastolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1252470/full

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