PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum

Abstract Parvalbumin-expressing inhibitory neurons (PV-INs) are critical for the balance and fine-tuning of complex neuronal circuits. Studies of PV-IN biology require tools for their specific labeling, targeting and manipulation. Among these, the Cre/LoxP system is the most popular in mice, with th...

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Bibliographic Details
Main Authors: Wendy Xueyi Wang, Julia Qiao, Julie L. Lefebvre
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-022-00972-1