Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes
Abstract Background Genetic studies have associated thousands of enhancers with breast cancer (BC). However, the vast majority have not been functionally characterized. Thus, it remains unclear how BC-associated enhancers contribute to cancer. Results Here, we perform single-cell CRISPRi screens of...
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
BMC
2025-01-01
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| سلاسل: | Genome Biology |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s13059-025-03474-0 |