Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway

Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway

BackgroundGlobally, esophageal cancer ranks as the seventh most common cancer. Esophageal squamous cell carcinoma (ESCC) is one of its major histological types. ESCC accounts for the vast majority of cases in China, and the mortality rate is high. Cisplatin, the standard adjuvant chemotherapy drug f...

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Bibliographic Details
Main Authors: Jida Guo, Shengqiang Zhang, Jun Wang, Pengfei Zhang, Tong Lu, Linyou Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
esophageal cancer
hinokiflavone
apoptosis
KEGG analysis
molecular docking
PI3K/AKT/mTOR signal pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.833719/full

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