Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis

Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis

Multiple sclerosis (MS) is a chronic demyelinating disease characterised by immune cell infiltration resulting in lesions that preferentially affect periventricular areas of the brain. Despite research efforts to define the role of various immune cells in MS pathogenesis, the focus has been on a few...

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Bibliographic Details
Main Authors: Sabela Rodríguez-Lorenzo, Lynn van Olst, Carla Rodriguez-Mogeda, Alwin Kamermans, Susanne MA van der Pol, Ernesto Rodríguez, Gijs Kooij, Helga E de Vries
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
multiple sclerosis
natural killer cells
single-cell mass cytometry
periventricular
choroid plexus
septum
Online Access:https://elifesciences.org/articles/73849

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