Therapeutic management of an IgA Nephropathy case and disease review

Inmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical...

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Main Authors: Bruno Lococo, Valeria Alberton, Bernarda Fazzini, Alejandra Smuclir Quevedo, Diego Morales, Ana Malvar
Format: Article
Language:Spanish
Published: Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires 2016-06-01
Series:Revista de Nefrología, Diálisis y Trasplante
Subjects:
Online Access:http://www.revistarenal.org.ar/index.php/rndt/article/view/66
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author Bruno Lococo
Valeria Alberton
Bernarda Fazzini
Alejandra Smuclir Quevedo
Diego Morales
Ana Malvar
author_facet Bruno Lococo
Valeria Alberton
Bernarda Fazzini
Alejandra Smuclir Quevedo
Diego Morales
Ana Malvar
author_sort Bruno Lococo
collection DOAJ
description Inmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical presentation is extremely variable and can vary from isolated microhematuria up to a severe damage of renal function due to superimposed extracapillary glomerulonephritis. Initially it was considered an entity with good prognosis, but over time and more knowledge about IgAN, it was shown that 20 to 30% of 20 years old patients evolved to end stage renal failure and other 20% had important renal function loss. In the present article we describe a case of a patient in whom we detected by chance renal damage markers in the urine, and then the histologic findings observed in renal biopsy, modified the prognosis and therapeutic procedure. From this clinical case, we performed an update on IgA Nephropathy.
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spelling doaj.art-8f82d29277964eb08e1a832b59ea1dac2022-12-21T18:51:08ZspaAsociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos AiresRevista de Nefrología, Diálisis y Trasplante0326-34282346-85482016-06-0136210812365Therapeutic management of an IgA Nephropathy case and disease reviewBruno Lococo0Valeria Alberton1Bernarda Fazzini2Alejandra Smuclir Quevedo3Diego Morales4Ana Malvar5Servicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Anatomía Patológica, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresInmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical presentation is extremely variable and can vary from isolated microhematuria up to a severe damage of renal function due to superimposed extracapillary glomerulonephritis. Initially it was considered an entity with good prognosis, but over time and more knowledge about IgAN, it was shown that 20 to 30% of 20 years old patients evolved to end stage renal failure and other 20% had important renal function loss. In the present article we describe a case of a patient in whom we detected by chance renal damage markers in the urine, and then the histologic findings observed in renal biopsy, modified the prognosis and therapeutic procedure. From this clinical case, we performed an update on IgA Nephropathy.http://www.revistarenal.org.ar/index.php/rndt/article/view/66nefropatía por inmunoglobulina AIgAenfermedad de Bergerpatogeniatratamiento
spellingShingle Bruno Lococo
Valeria Alberton
Bernarda Fazzini
Alejandra Smuclir Quevedo
Diego Morales
Ana Malvar
Therapeutic management of an IgA Nephropathy case and disease review
Revista de Nefrología, Diálisis y Trasplante
nefropatía por inmunoglobulina A
IgA
enfermedad de Berger
patogenia
tratamiento
title Therapeutic management of an IgA Nephropathy case and disease review
title_full Therapeutic management of an IgA Nephropathy case and disease review
title_fullStr Therapeutic management of an IgA Nephropathy case and disease review
title_full_unstemmed Therapeutic management of an IgA Nephropathy case and disease review
title_short Therapeutic management of an IgA Nephropathy case and disease review
title_sort therapeutic management of an iga nephropathy case and disease review
topic nefropatía por inmunoglobulina A
IgA
enfermedad de Berger
patogenia
tratamiento
url http://www.revistarenal.org.ar/index.php/rndt/article/view/66
work_keys_str_mv AT brunolococo therapeuticmanagementofaniganephropathycaseanddiseasereview
AT valeriaalberton therapeuticmanagementofaniganephropathycaseanddiseasereview
AT bernardafazzini therapeuticmanagementofaniganephropathycaseanddiseasereview
AT alejandrasmuclirquevedo therapeuticmanagementofaniganephropathycaseanddiseasereview
AT diegomorales therapeuticmanagementofaniganephropathycaseanddiseasereview
AT anamalvar therapeuticmanagementofaniganephropathycaseanddiseasereview