Therapeutic management of an IgA Nephropathy case and disease review
Inmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical...
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Format: | Article |
Language: | Spanish |
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Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires
2016-06-01
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Series: | Revista de Nefrología, Diálisis y Trasplante |
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Online Access: | http://www.revistarenal.org.ar/index.php/rndt/article/view/66 |
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author | Bruno Lococo Valeria Alberton Bernarda Fazzini Alejandra Smuclir Quevedo Diego Morales Ana Malvar |
author_facet | Bruno Lococo Valeria Alberton Bernarda Fazzini Alejandra Smuclir Quevedo Diego Morales Ana Malvar |
author_sort | Bruno Lococo |
collection | DOAJ |
description | Inmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical presentation is extremely variable and can vary from isolated microhematuria up to a severe damage of renal function due to superimposed extracapillary glomerulonephritis. Initially it was considered an entity with good prognosis, but over time and more knowledge about IgAN, it was shown that 20 to 30% of 20 years old patients evolved to end stage renal failure and other 20% had important renal function loss. In the present article we describe a case of a patient in whom we detected by chance renal damage markers in the urine, and then the histologic findings observed in renal biopsy, modified the prognosis and therapeutic procedure. From this clinical case, we performed an update on IgA Nephropathy. |
first_indexed | 2024-12-21T20:34:53Z |
format | Article |
id | doaj.art-8f82d29277964eb08e1a832b59ea1dac |
institution | Directory Open Access Journal |
issn | 0326-3428 2346-8548 |
language | Spanish |
last_indexed | 2024-12-21T20:34:53Z |
publishDate | 2016-06-01 |
publisher | Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires |
record_format | Article |
series | Revista de Nefrología, Diálisis y Trasplante |
spelling | doaj.art-8f82d29277964eb08e1a832b59ea1dac2022-12-21T18:51:08ZspaAsociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos AiresRevista de Nefrología, Diálisis y Trasplante0326-34282346-85482016-06-0136210812365Therapeutic management of an IgA Nephropathy case and disease reviewBruno Lococo0Valeria Alberton1Bernarda Fazzini2Alejandra Smuclir Quevedo3Diego Morales4Ana Malvar5Servicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Anatomía Patológica, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresServicio de Nefrología, Hospital General de Agudos Dr. Juan A. Fernández, Buenos AiresInmunoglobulin A (NIgA) Nephropathy also known as Berger disease, was described for the first time in 1968 by Berger and Hinglais. It is a heterogeneous disease, not only from clinical point of view but also from the histologicalone. Characterized by the presence of IgA mesangials deposits. Clinical presentation is extremely variable and can vary from isolated microhematuria up to a severe damage of renal function due to superimposed extracapillary glomerulonephritis. Initially it was considered an entity with good prognosis, but over time and more knowledge about IgAN, it was shown that 20 to 30% of 20 years old patients evolved to end stage renal failure and other 20% had important renal function loss. In the present article we describe a case of a patient in whom we detected by chance renal damage markers in the urine, and then the histologic findings observed in renal biopsy, modified the prognosis and therapeutic procedure. From this clinical case, we performed an update on IgA Nephropathy.http://www.revistarenal.org.ar/index.php/rndt/article/view/66nefropatía por inmunoglobulina AIgAenfermedad de Bergerpatogeniatratamiento |
spellingShingle | Bruno Lococo Valeria Alberton Bernarda Fazzini Alejandra Smuclir Quevedo Diego Morales Ana Malvar Therapeutic management of an IgA Nephropathy case and disease review Revista de Nefrología, Diálisis y Trasplante nefropatía por inmunoglobulina A IgA enfermedad de Berger patogenia tratamiento |
title | Therapeutic management of an IgA Nephropathy case and disease review |
title_full | Therapeutic management of an IgA Nephropathy case and disease review |
title_fullStr | Therapeutic management of an IgA Nephropathy case and disease review |
title_full_unstemmed | Therapeutic management of an IgA Nephropathy case and disease review |
title_short | Therapeutic management of an IgA Nephropathy case and disease review |
title_sort | therapeutic management of an iga nephropathy case and disease review |
topic | nefropatía por inmunoglobulina A IgA enfermedad de Berger patogenia tratamiento |
url | http://www.revistarenal.org.ar/index.php/rndt/article/view/66 |
work_keys_str_mv | AT brunolococo therapeuticmanagementofaniganephropathycaseanddiseasereview AT valeriaalberton therapeuticmanagementofaniganephropathycaseanddiseasereview AT bernardafazzini therapeuticmanagementofaniganephropathycaseanddiseasereview AT alejandrasmuclirquevedo therapeuticmanagementofaniganephropathycaseanddiseasereview AT diegomorales therapeuticmanagementofaniganephropathycaseanddiseasereview AT anamalvar therapeuticmanagementofaniganephropathycaseanddiseasereview |